TcYC6_0115610

tubulin-specific chaperone, putative
Trypanosoma cruzi Y C6 OG6: OG6_102852 OG7: OG7_0002326 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0052760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0009190 ⚠
Tetratricopeptide repeat, putative
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0030670 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0109490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0103200 ⚠
hypothetical protein
— OG7
TcYC6_0114770 ⚠
putative intraflagellar transport protein 140
— OG7
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0113430 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0083610 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127460 ⚠
fibrillarin, putative
— OG7
TcYC6_0091650 ⚠
proteasome beta 7 subunit, putative
— OG7
TcYC6_0037010 ⚠
oligopeptidase b
— OG7
TcYC6_0013810 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcYC6_0025000 ⚠
predicted tetratricopeptide repeat protein
— OG7
TcYC6_0043480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0074570 ⚠
putative calpain cysteine peptidase
— OG7
TcYC6_0074560 ⚠
putative calpain-like cysteine peptidase
— OG7
TcYC6_0074550 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— OG7
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— OG7
TcYC6_0061620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018570 ⚠
tc40 antigen-like, putative
— OG7
TcYC6_0042470 ⚠
paraflagellar rod protein, putative
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0076120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016180 ⚠
dynein heavy chain, putative
— OG7
TcYC6_0028100 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0084140 ⚠
Eukaryotic initiation factor 4A-1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.