TcYC6_0074560

putative calpain-like cysteine peptidase
Trypanosoma cruzi Y C6 OG6: OG6_115879 OG7: OG7_0021639 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0107380 ⚠
Calpain-like protein 2
— OG6
TcYC6_0126130 ⚠
60S ribosomal protein L37a, putative
— Both
TcYC6_0066080 ⚠
Mitochondrial ribosomal protein L9
— Both
TcYC6_0021970 ⚠
mitochondrial RNA binding complex 1 subunit,
— Both
TcYC6_0074570 ⚠
putative calpain cysteine peptidase
— +2 more Both
TcYC6_0107890 ⚠
Mitochondrial ribosomal protein L3
— Both
TcYC6_0065690 ⚠
Mitochondrial ribosomal protein L49
— Both
TcYC6_0074550 ⚠
cysteine peptidase, Clan CA, family C2, putat
— +2 more Both
TcYC6_0021810 ⚠
40S ribosomal protein S11, putative
— Both
TcYC6_0070060 ⚠
30S Ribosomal protein S17, putative
— Both
TcYC6_0005470 ⚠
40S ribosomal protein S11, putative
— Both
TcYC6_0022100 ⚠
60S ribosomal protein L37a, putative
— Both
TcYC6_0034540 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0037090 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
TcYC6_0072770 ⚠
Unc104-like kinesin
— OG6
TcYC6_0057990 ⚠
small GTP-binding protein, putative
— Both
TcYC6_0067120 ⚠
mitochondrial ribosomal protein L15
— Both
TcYC6_0127620 ⚠
LSU ribosomal protein, mitochondrial, putativ
— Both
TcYC6_0084640 ⚠
pseudouridylate synthase-like protein, putati
— Both
TcYC6_0102690 ⚠
40S ribosomal protein S4, putative
— Both
TcYC6_0102700 ⚠
40S ribosomal protein S4, putative
— Both
TcYC6_0093970 ⚠
hypothetical protein, conserved
— Both
TcYC6_0097690 ⚠
LSU ribosomal protein, mitochondrial, putativ
— Both
TcYC6_0106390 ⚠
hypothetical protein, conserved
— Both
TcYC6_0046170 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0072620 ⚠
GTPase protein
— OG7
TcYC6_0015520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0041950 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0058520 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG7
TcYC6_0115370 ⚠
60S ribosomal protein L7, putative
— OG7
TcYC6_0117290 ⚠
zinc finger protein 3
— OG7
TcYC6_0034870 ⚠
zinc finger (CCCH type) protein, putative
— OG7
TcYC6_0047330 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcYC6_0128020 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0032610 ⚠
hypothetical protein, conserved
— Both
TcYC6_0050970 ⚠
hypothetical protein
— OG7
TcYC6_0009330 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0011320 ⚠
60S ribosomal protein L14, putative
— Both
TcYC6_0094060 ⚠
60S ribosomal protein L14, putative
— Both
TcYC6_0175450 ⚠
hypothetical protein, conserved
— Both
TcYC6_0054260 ⚠
mitochondrial ribosomal protein L17
— Both
TcYC6_0042940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0024730 ⚠
Mitochondrial 39-S ribosomal protein L47 (MRP
— Both
TcYC6_0000050 ⚠
hypothetical protein, conserved
— Both
TcYC6_0048360 ⚠
hypothetical protein, conserved
— Both
TcYC6_0071730 ⚠
60S ribosomal protein L37, putative
— Both
TcYC6_0057370 ⚠
60S ribosomal protein L7, putative
— Both
TcYC6_0110880 ⚠
60S ribosomal protein L13, putative
— Both
TcYC6_0069390 ⚠
60S ribosomal subunit protein L31, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.