TcYC6_0102700

40S ribosomal protein S4, putative

Trypanosoma cruzi Y C6 OG6: OG6_100732 OG7: OG7_0004517 155 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 155 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0028020 ⚠ 40S ribosomal protein S3, putative	—	OG6 TCSYLVIO_000304 ↔ TCSYLVIO_003037 OG6 Tb927.11.3590 ↔ Tb927.9.6070 OG6 LdBPK_131120.1 ↔ LdBPK_330960.1 OG7 TCSYLVIO_000304 ↔ TCSYLVIO_003037 +2 more	Both
TcYC6_0125180 ⚠ 40S ribosomal protein S3, putative	—	OG6 TCSYLVIO_000304 ↔ TCSYLVIO_003037 OG6 Tb927.11.3590 ↔ Tb927.9.6070 OG6 LdBPK_131120.1 ↔ LdBPK_330960.1 OG7 TCSYLVIO_000304 ↔ TCSYLVIO_003037 +2 more	Both
TcYC6_0005700 ⚠ 40S ribosomal protein SA, putative	—	OG6 Tb927.11.10790 ↔ Tb927.11.3590 OG6 TCSYLVIO_003037 ↔ TCSYLVIO_008297 OG6 LdBPK_131120.1 ↔ LdBPK_365240.1 OG7 TCSYLVIO_003037 ↔ TCSYLVIO_008297 +2 more	Both
TcYC6_0005800 ⚠ 40S ribosomal protein SA, putative	—	OG6 Tb927.11.10790 ↔ Tb927.11.3590 OG6 TCSYLVIO_003037 ↔ TCSYLVIO_008297 OG6 LdBPK_131120.1 ↔ LdBPK_365240.1 OG7 TCSYLVIO_003037 ↔ TCSYLVIO_008297 +2 more	Both
TcYC6_0100010 ⚠ 60S ribosomal protein L7a, putative	—	OG6 LdBPK_070550.1 ↔ LdBPK_131120.1 OG6 Tb927.11.3590 ↔ Tb927.8.1330 OG7 Tb927.11.3590 ↔ Tb927.8.1330 OG7 LdBPK_070550.1 ↔ LdBPK_131120.1	Both
TcYC6_0034850 ⚠ 60S ribosomal protein L13a, putative	—	OG6 Tb927.11.3600 ↔ Tb927.5.1610 OG6 Tb927.11.3590 ↔ Tb927.4.3550 OG6 LdBPK_131120.1 ↔ LdBPK_340910.1 OG7 Tb927.11.3600 ↔ Tb927.5.1610 +2 more	Both
TcYC6_0057370 ⚠ 60S ribosomal protein L7, putative	—	OG6 Tb927.11.3590 ↔ Tb927.7.1730 OG6 LdBPK_131120.1 ↔ LdBPK_260160.1 OG7 Tb927.11.3590 ↔ Tb927.7.1730 OG7 LdBPK_131120.1 ↔ LdBPK_260160.1	Both
TcYC6_0126130 ⚠ 60S ribosomal protein L37a, putative	—	OG6 LdBPK_131120.1 ↔ LdBPK_212190.1 OG6 Tb927.10.220 ↔ Tb927.11.3590 OG7 Tb927.10.220 ↔ Tb927.11.3590 OG7 LdBPK_131120.1 ↔ LdBPK_212190.1	Both
TcYC6_0083720 ⚠ 40S ribosomal protein S8, putative	—	OG6 Tb927.11.3600 ↔ Tb927.8.6160 OG6 Tb927.11.3590 ↔ Tb927.8.6150 OG6 TCSYLVIO_001300 ↔ TCSYLVIO_003037 OG7 TCSYLVIO_001300 ↔ TCSYLVIO_003037 +2 more	Both
TcYC6_0087420 ⚠ 60S ribosomal protein L13a, putative	—	OG6 Tb927.11.3600 ↔ Tb927.5.1610 OG6 Tb927.11.3590 ↔ Tb927.4.3550 OG6 LdBPK_131120.1 ↔ LdBPK_340910.1 OG7 Tb927.11.3600 ↔ Tb927.5.1610 +2 more	Both
TcYC6_0022100 ⚠ 60S ribosomal protein L37a, putative	—	OG6 LdBPK_131120.1 ↔ LdBPK_212190.1 OG6 Tb927.10.220 ↔ Tb927.11.3590 OG7 Tb927.10.220 ↔ Tb927.11.3590 OG7 LdBPK_131120.1 ↔ LdBPK_212190.1	Both
TcYC6_0083710 ⚠ 40S ribosomal protein S8, putative	—	OG6 Tb927.11.3600 ↔ Tb927.8.6160 OG6 Tb927.11.3590 ↔ Tb927.8.6150 OG6 TCSYLVIO_001300 ↔ TCSYLVIO_003037 OG7 TCSYLVIO_001300 ↔ TCSYLVIO_003037 +2 more	Both
TcYC6_0110870 ⚠ 60S ribosomal protein L13, putative	—	OG6 Tb927.11.3590 ↔ Tb927.3.3310 OG6 LdBPK_131120.1 ↔ LdBPK_292580.1 OG6 LdBPK_131120.1 ↔ LdBPK_292570.1 OG7 Tb927.11.3590 ↔ Tb927.3.3310 +2 more	Both
TcYC6_0089940 ⚠ ribosomal protein S19, putative	—	OG6 Tb927.11.3600 ↔ Tb927.4.1860 OG6 Tb927.11.3590 ↔ Tb927.4.1860 OG6 LdBPK_131120.1 ↔ LdBPK_342620.1 OG7 Tb927.11.3600 ↔ Tb927.4.1860 +2 more	Both
TcYC6_0079800 ⚠ 40S ribosomal protein S18, putative	—	OG6 Tb927.10.5330 ↔ Tb927.11.3590 OG6 LdBPK_131120.1 ↔ LdBPK_360990.1 OG7 Tb927.10.5330 ↔ Tb927.11.3590 OG7 LdBPK_131120.1 ↔ LdBPK_360990.1	Both
TcYC6_0079810 ⚠ 40S ribosomal protein S18, putative	—	OG6 Tb927.10.5330 ↔ Tb927.11.3590 OG6 LdBPK_131120.1 ↔ LdBPK_360990.1 OG7 Tb927.10.5330 ↔ Tb927.11.3590 OG7 LdBPK_131120.1 ↔ LdBPK_360990.1	Both
TcYC6_0100020 ⚠ 60S ribosomal protein L7a, putative	—	OG6 LdBPK_070550.1 ↔ LdBPK_131120.1 OG6 Tb927.11.3590 ↔ Tb927.8.1330 OG7 Tb927.11.3590 ↔ Tb927.8.1330 OG7 LdBPK_070550.1 ↔ LdBPK_131120.1	Both
TcYC6_0084480 ⚠ ribosomal protein S7, putative	—	OG6 TCSYLVIO_003037 ↔ TCSYLVIO_003444 OG6 Tb927.11.3590 ↔ Tb927.9.3990 OG7 TCSYLVIO_003037 ↔ TCSYLVIO_003444 OG7 Tb927.11.3590 ↔ Tb927.9.3990	Both
TcYC6_0084470 ⚠ ribosomal protein S7, putative	—	OG6 TCSYLVIO_003037 ↔ TCSYLVIO_003444 OG6 Tb927.11.3590 ↔ Tb927.9.3990 OG7 TCSYLVIO_003037 ↔ TCSYLVIO_003444 OG7 Tb927.11.3590 ↔ Tb927.9.3990	Both
TcYC6_0058170 ⚠ 60S ribosomal protein L7, putative	—	OG6 Tb927.11.3590 ↔ Tb927.7.1730 OG6 LdBPK_131120.1 ↔ LdBPK_260160.1 OG7 Tb927.11.3590 ↔ Tb927.7.1730 OG7 LdBPK_131120.1 ↔ LdBPK_260160.1	Both
TcYC6_0115370 ⚠ 60S ribosomal protein L7, putative	—	OG7 Tb927.11.3590 ↔ Tb927.7.1730 OG7 LdBPK_131120.1 ↔ LdBPK_260160.1	OG7
TcYC6_0067390 ⚠ 40S ribosomal protein S6, putative	—	OG6 TCSYLVIO_001068 ↔ TCSYLVIO_003037 OG6 Tb927.10.190 ↔ Tb927.11.3590 OG7 TCSYLVIO_001068 ↔ TCSYLVIO_003037 OG7 Tb927.10.190 ↔ Tb927.11.3590	Both
TcYC6_0058510 ⚠ 40S ribosomal protein S16, putative	—	OG6 TCSYLVIO_002326 ↔ TCSYLVIO_003037 OG6 Tb927.11.3590 ↔ Tb927.7.1040 OG6 Tb927.11.3600 ↔ Tb927.7.1050 OG7 Tb927.11.3590 ↔ Tb927.7.1040 +2 more	Both
TcYC6_0110880 ⚠ 60S ribosomal protein L13, putative	—	OG6 Tb927.11.3590 ↔ Tb927.3.3310 OG6 LdBPK_131120.1 ↔ LdBPK_292580.1 OG6 LdBPK_131120.1 ↔ LdBPK_292570.1 OG7 Tb927.11.3590 ↔ Tb927.3.3310 +2 more	Both
TcYC6_0057980 ⚠ 40S ribosomal protein S16, putative	—	OG6 TCSYLVIO_002326 ↔ TCSYLVIO_003037 OG6 Tb927.11.3590 ↔ Tb927.7.1040 OG6 Tb927.11.3600 ↔ Tb927.7.1050 OG7 Tb927.11.3590 ↔ Tb927.7.1040 +2 more	Both
TcYC6_0090880 ⚠ ribosomal protein L21E (60S), putative	—	OG6 Tb927.11.3590 ↔ Tb927.11.680 OG6 Tb927.11.3600 ↔ Tb927.4.1100 OG7 Tb927.11.3590 ↔ Tb927.11.680 OG7 Tb927.11.3600 ↔ Tb927.4.1100	Both
TcYC6_0110050 ⚠ 40S ribosomal protein S15A, putative	—	OG6 Tb927.11.3590 ↔ Tb927.11.6140 OG7 Tb927.11.3590 ↔ Tb927.11.6140	Both
TcYC6_0006450 ⚠ 2-oxoglutarate dehydrogenase E1 component, pu	—	OG6 LdBPK_131120.1 ↔ LdBPK_363630.1 OG7 LdBPK_131120.1 ↔ LdBPK_363630.1	Both
TcYC6_0034540 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_131120.1 ↔ LdBPK_270510.1	OG6
TcYC6_0089570 ⚠ ribosomal protein l35a, putative	—	OG6 Tb927.11.3590 ↔ Tb927.4.2180 OG7 Tb927.11.3590 ↔ Tb927.4.2180	Both
TcYC6_0074570 ⚠ putative calpain cysteine peptidase	—	OG6 LdBPK_131120.1 ↔ LdBPK_270510.1 OG7 LdBPK_131120.1 ↔ LdBPK_270510.1	Both
TcYC6_0071730 ⚠ 60S ribosomal protein L37, putative	—	OG6 LdBPK_131120.1 ↔ LdBPK_332070.1 OG7 LdBPK_131120.1 ↔ LdBPK_332070.1	Both
TcYC6_0072190 ⚠ 60S ribosomal protein L37, putative	—	OG6 LdBPK_131120.1 ↔ LdBPK_332070.1 OG7 LdBPK_131120.1 ↔ LdBPK_332070.1	Both
TcYC6_0074560 ⚠ putative calpain-like cysteine peptidase	—	OG6 LdBPK_131120.1 ↔ LdBPK_270510.1 OG7 LdBPK_131120.1 ↔ LdBPK_270510.1	Both
TcYC6_0075690 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_131120.1 ↔ LdBPK_272450.1 OG7 LdBPK_131120.1 ↔ LdBPK_272450.1	Both
TcYC6_0094060 ⚠ 60S ribosomal protein L14, putative	—	OG6 LdBPK_131120.1 ↔ LdBPK_221370.1 OG7 LdBPK_131120.1 ↔ LdBPK_221370.1	Both
TcYC6_0099020 ⚠ ribosomal protein L15, putative	—	OG6 Tb927.11.3590 ↔ Tb927.9.15190 OG7 Tb927.11.3590 ↔ Tb927.9.15190	Both
TcYC6_0043550 ⚠ 40S ribosomal protein S21, putative	—	OG6 Tb927.11.3590 ↔ Tb927.11.6500 OG7 Tb927.11.3590 ↔ Tb927.11.6500	Both
TcYC6_0022430 ⚠ 40S ribosomal protein S23, putative	—	OG6 Tb927.10.1080 ↔ Tb927.11.3590 OG7 Tb927.10.1080 ↔ Tb927.11.3590	Both
TcYC6_0107020 ⚠ putative mitochondrial RNA binding protein	—	OG6 TCSYLVIO_002960 ↔ TCSYLVIO_003037 OG7 TCSYLVIO_002960 ↔ TCSYLVIO_003037	Both
TcYC6_0116770 ⚠ 60S ribosomal protein L34, putative	—	OG6 Tb927.11.3600 ↔ Tb927.11.9730 OG7 Tb927.11.3600 ↔ Tb927.11.9730	Both
TcYC6_0127680 ⚠ 40S ribosomal protein S24E, putative	—	OG6 Tb927.10.7330 ↔ Tb927.11.3590 OG7 Tb927.10.7330 ↔ Tb927.11.3590	Both
TcYC6_0022440 ⚠ 40S ribosomal protein S23, putative	—	OG6 Tb927.10.1080 ↔ Tb927.11.3590 OG7 Tb927.10.1080 ↔ Tb927.11.3590	Both
TcYC6_0077240 ⚠ heterogeneous nuclear ribonucleoprotein H/F,	—	OG6 TCSYLVIO_000392 ↔ TCSYLVIO_003037 OG7 TCSYLVIO_000392 ↔ TCSYLVIO_003037	Both
TcYC6_0046290 ⚠ 60S ribosomal protein L19	—	OG6 Tb927.11.3600 ↔ Tb927.7.5020 OG7 Tb927.11.3600 ↔ Tb927.7.5020	Both
TcYC6_0090030 ⚠ ribosomal protein L3, putative	—	OG6 Tb927.11.3590 ↔ Tb927.4.1790 OG7 Tb927.11.3590 ↔ Tb927.4.1790	Both
TcYC6_0028310 ⚠ Eukaryotic translation initiation factor 4 ga	—	OG6 LdBPK_131120.1 ↔ LdBPK_151340.1 OG7 LdBPK_131120.1 ↔ LdBPK_151340.1	Both
TcYC6_0107970 ⚠ putative membrane associated protein	—	OG6 LdBPK_131120.1 ↔ LdBPK_290110.1 OG7 LdBPK_131120.1 ↔ LdBPK_290110.1	Both
TcYC6_0117190 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_131120.1 ↔ LdBPK_310090.1 OG7 LdBPK_131120.1 ↔ LdBPK_310090.1	Both
TcYC6_0127690 ⚠ 40S ribosomal protein S24E, putative	—	OG6 Tb927.10.7330 ↔ Tb927.11.3590 OG7 Tb927.10.7330 ↔ Tb927.11.3590	Both

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