TcYC6_0124120

Anaphase-promoting complex, cyclosome, subunit 3/TPR repeat, putative
Trypanosoma cruzi Y C6 OG6: OG6_101939 OG7: OG7_0003813 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0113480 ⚠
anaphase promoting complex subunit 10, putati
— +2 more Both
TcYC6_0081840 ⚠
hypothetical protein, conserved
— +2 more Both
TcYC6_0096930 ⚠
cyclosome subunit, putative
— +2 more Both
TcYC6_0045470 ⚠
hypothetical protein, conserved
— Both
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— Both
TcYC6_0095570 ⚠
CDC16, putative
— +2 more Both
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0175230 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0094210 ⚠
ccr4-not transcription complex subunit
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0026400 ⚠
hypothetical protein
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0090570 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0127410 ⚠
protein kinase, putative
— OG7
TcYC6_0032440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0017100 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcYC6_0083610 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0037340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009850 ⚠
RING-H2 zinc finger, putative
— OG7
TcYC6_0066460 ⚠
RING-H2 zinc finger, putative
— OG7
TcYC6_0066470 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0050260 ⚠
Flagellar Member 7
— OG7
TcYC6_0021450 ⚠
Tetratricopeptide repeat, putative
— OG7
TcYC6_0065880 ⚠
Autophagy protein Apg6, putative
— OG7
TcYC6_0026390 ⚠
hypothetical protein
— OG7
TcYC6_0016180 ⚠
dynein heavy chain, putative
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0095490 ⚠
pdz domain containing protein, putative
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0079740 ⚠
intraflagellar transport protein 122, putativ
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022010 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0048030 ⚠
Kinetochore interacting protein 5
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0109490 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.