TcYC6_0043860

3-methylcrotonoyl-CoA carboxylase beta subunit, putative
Trypanosoma cruzi Y C6 OG6: OG6_101933 OG7: OG7_0003085 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0103770
3-methylcrotonyl-CoA carboxylase, putative
— Both
TcYC6_0021740
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
TcYC6_0097400
hypothetical protein, conserved
— Both
TcYC6_0016780
transmembrane protein, conserved
— Both
TcYC6_0046450
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcYC6_0024250 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0029820 ⚠
hypothetical protein
— Both
TcYC6_0029810 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0024260 ⚠
hypothetical protein
— Both
TcYC6_0004060 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0025640 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcYC6_0048370 ⚠
GMP reductase
— OG6
TcYC6_0112960 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcYC6_0122540
AAA domain containing protein, putative
— Both
TcYC6_0065880
Autophagy protein Apg6, putative
— OG7
TcYC6_0015620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012460 ⚠
leucine rich repeat
— OG7
TcYC6_0074870
hypothetical protein, conserved
— OG7
TcYC6_0127410
protein kinase, putative
— OG7
TcYC6_0081220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0064370 ⚠
translation initiation factor 2b, delta subun
— OG7
TcYC6_0073890 ⚠
translation initiation factor eIF2B subunit-l
— OG7
TcYC6_0060200
hypothetical protein, conserved
— OG7
TcYC6_0037000
hypothetical protein
— OG7
TcYC6_0057680
hypothetical protein, conserved
— OG6
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0066520
glutamine hydrolysing (not ammonia-dependent)
— Both
TcYC6_0007440
ATP synthase, putative
— Both
TcYC6_0104900 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcYC6_0104890 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0043490
hypothetical protein, conserved
— Both
TcYC6_0113410
hypothetical protein, conserved
— Both
TcYC6_0009410
Vps51/Vps67, putative
— Both
TcYC6_0053360
conserved protein
— OG6
TcYC6_0108520
bardet-biedl syndrome 7 protein
— Both
TcYC6_0096490
kinesin, putative
— Both
TcYC6_0013950
leucine-rich repeat protein (LRRP), putative
— Both
TcYC6_0053070
Bardet-Biedl syndrome 9 protein
— Both
TcYC6_0095410
Bardet-Biedl syndrome 2 protein
— Both
TcYC6_0061720 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcYC6_0034490
hypothetical protein, conserved
— Both
TcYC6_0031560
(H+)-ATPase G subunit
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.