TcYC6_0029810

delta-1-pyrroline-5-carboxylate dehydrogenase
Trypanosoma cruzi Y C6 OG6: OG6_102275 OG7: OG7_0000710 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0085630 ⚠
cytochrome c oxidase subunit V, putative
— Both
TcYC6_0103930 ⚠
acetyl-CoA carboxylase
— Both
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcYC6_0032470 ⚠
peroxidoxin
— Both
TcYC6_0028120 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcYC6_0046920 ⚠
vacuolar ATP synthase subunit d
— Both
TcYC6_0046450 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
TcYC6_0011990 ⚠
Vacuolar proton pump subunit B, putative
— Both
TcYC6_0007440 ⚠
ATP synthase, putative
— Both
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcYC6_0043860 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TcYC6_0007280 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcYC6_0028100 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0060480 ⚠
ATP synthase subunit, putative
— Both
TcYC6_0009670 ⚠
hexokinase, putative
— Both
TcYC6_0121450 ⚠
prolyl endopeptidase
— OG7
TcYC6_0098790 ⚠
T-complex protein 11, putative
— Both
TcYC6_0069370 ⚠
hypothetical protein
— Both
TcYC6_0016170 ⚠
deoxyhypusine synthase
— Both
TcYC6_0037010 ⚠
oligopeptidase b
— Both
TcYC6_0007230 ⚠
glycyl-tRNA synthetase, putative
— Both
TcYC6_0047190 ⚠
hypothetical protein, conserved
— Both
TcYC6_0112510 ⚠
deoxyhypusine synthase, putative
— Both
TcYC6_0103830 ⚠
peptidase, putative
— Both
TcYC6_0098470 ⚠
valyl-tRNA synthetase, putative
— Both
TcYC6_0102550 ⚠
leucyl-tRNA synthetase, putative
— Both
TcYC6_0013810 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcYC6_0111000 ⚠
Serine/threonine-protein kinase NEK7, putativ
— OG6
TcYC6_0093110 ⚠
hypothetical protein
— Both
TcYC6_0031560 ⚠
(H+)-ATPase G subunit
— Both
TcYC6_0028110 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0021670 ⚠
ATP synthase, putative
— Both
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
TcYC6_0028130 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0090930 ⚠
V-type ATPase, A subunit, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.