TcYC6_0112510

deoxyhypusine synthase, putative

Trypanosoma cruzi Y C6 OG6: OG6_101093 OG7: OG7_0005231 151 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 151 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0016170 ⚠ deoxyhypusine synthase	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
TcYC6_0075720 ⚠ calcium/calmodulin-dependent protein kinase,	—	OG7 TCSYLVIO_005149 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005149	OG7
TcYC6_0092440 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007258	Both
TcYC6_0000270 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
TcYC6_0013810 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
TcYC6_0037010 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
TcYC6_0093770 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
TcYC6_0093110 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
TcYC6_0057100 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002362 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002362 ↔ TCSYLVIO_004558	Both
TcYC6_0057340 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
TcYC6_0075790 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
TcYC6_0080780 ⚠ stress-inducible protein STI1-like, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
TcYC6_0094080 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
TcYC6_0110440 ⚠ UDP-glucose:glycoprotein glucosyltransferase	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
TcYC6_0000250 ⚠ Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
TcYC6_0044260 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TcYC6_0111400 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TcYC6_0042390 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
TcYC6_0079830 ⚠ SNF1-related protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0012450 ⚠ Small Surface Antigen	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0093270 ⚠ calcium/calmodulin-dependent protein kinase,	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0078640 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0115830 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0044850 ⚠ exosome complex exonuclease RRP44p-like	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
TcYC6_0100460 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0009920 ⚠ CAMK/CAMKL pseudokinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0046790 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
TcYC6_0024770 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
TcYC6_0090570 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
TcYC6_0040620 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TcYC6_0109080 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TcYC6_0058570 ⚠ cytochrome b5-like Heme/Steroid binding domai	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TcYC6_0049170 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TcYC6_0043870 ⚠ cytochrome b5	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TcYC6_0124530 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TcYC6_0004090 ⚠ ABC transporter, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TcYC6_0002740 ⚠ ABC transporter, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TcYC6_0024170 ⚠ ABC transporter, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TcYC6_0029650 ⚠ ABC transporter, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TcYC6_0095530 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010327	OG7
TcYC6_0069010 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	OG7
TcYC6_0116460 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_004998	OG7
TcYC6_0048880 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_004998	OG7
TcYC6_0010170 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006877	OG7
TcYC6_0121450 ⚠ prolyl endopeptidase	—	OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	OG7
TcYC6_0082630 ⚠ translation initiation factor IF-2, putative	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	OG7
TcYC6_0142810 ⚠ retrotransposon hot spot (RHS) protein, putat	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010257 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010257	OG7
TcYC6_0010370 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
TcYC6_0142880 ⚠ retrotransposon hot spot (RHS) protein, putat	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010257 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010257	OG7
TcYC6_0092990 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7

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