TcYC6_0085630

cytochrome c oxidase subunit V, putative
Trypanosoma cruzi Y C6 OG6: OG6_147143 OG7: OG7_0043911 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0028110 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0043250
hypothetical protein, conserved
— Both
TcYC6_0000580 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000570 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000560 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0024250 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0000590 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000100 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000110 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0029820 ⚠
hypothetical protein
— Both
TcYC6_0029810 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0024260 ⚠
hypothetical protein
— Both
TcYC6_0004060 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0074230 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
TcYC6_0083800
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TcYC6_0006450 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
TcYC6_0028130 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0032470 ⚠
peroxidoxin
— Both
TcYC6_0028100 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0028120 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0058720 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcYC6_0058650 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcYC6_0074410
Mitochondrial ATP synthase subunit, putative
— Both
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0112720 ⚠
malate dehydrogenase, putative
— OG7
TcYC6_0091000 ⚠
serine-palmitoyl-CoA transferase
— OG7
TcYC6_0046750 ⚠
serine palmitoyltransferase, putative
— OG7
TcYC6_0041980 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0101770
SURF1 family, putative
— Both
TcYC6_0083900 ⚠
2-amino-3-ketobutyrate coenzyme A ligase, put
— Both
TcYC6_0083870 ⚠
2-amino-3-ketobutyrate coenzyme A ligase, put
— Both
TcYC6_0117910
ATP synthase subunit beta, mitochondrial
— Both
TcYC6_0112730 ⚠
malate dehydrogenase
— Both
TcYC6_0042030 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0042040 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0041990 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0041970 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0042020 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0042010 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0042000 ⚠
ATP synthase F1, alpha subunit
— Both
TcYC6_0115220
hypothetical protein, conserved
— Both
TcYC6_0044570
hypothetical protein, conserved
— Both
TcYC6_0106380
cytochrome c oxidase VIII (COX VIII), putativ
— Both
TcYC6_0083060
Succinate dehydrogenase [ubiquinone] flavopro
— Both
TcYC6_0080260
hypothetical protein, conserved
— Both
TcYC6_0013590
P27 protein, putative
— Both
TcYC6_0032770 ⚠
cytochrome c oxidase subunit 10, putative
— Both
TcYC6_0032810 ⚠
cytochrome c oxidase subunit 10, putative
— Both
TcYC6_0066570 ⚠
succinate dehydrogenase subunit
— Both
TcYC6_0054530 ⚠
succinate dehydrogenase subunit
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.