TcYC6_0100560

Domain of unknown function (DUF3437), putative
Trypanosoma cruzi Y C6 OG6: OG6_172390 OG7: OG7_0052363 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0072080
hypothetical protein, conserved
— OG7
TcYC6_0095370
hypothetical protein, conserved
— OG7
TcYC6_0116560
prolyl-tRNA synthetase, putative
— OG7
TcYC6_0022010
hypothetical protein, conserved
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0061220 ⚠
helicase, putative
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0060680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcYC6_0040300 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0110770
aspartyl aminopeptidase, putative
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0040350 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcYC6_0061280 ⚠
helicase, putative
— OG7
TcYC6_0101260
hypothetical protein, conserved
— OG7
TcYC6_0077260
translation initiation factor IF-2, putative
— OG7
TcYC6_0083670
tubulin folding cofactor D, putative
— OG7
TcYC6_0116260
putative 5-oxoprolinase
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0045680 ⚠
TLD, putative
— OG7
TcYC6_0126250 ⚠
PIF1 helicase-like protein
— OG7
TcYC6_0111640 ⚠
putative ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0043360
PUB domain containing protein, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0107960 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009900
vacuolar protein sorting-associated protein 3
— OG7
TcYC6_0061260 ⚠
helicase, putative
— OG7
TcYC6_0071320
hypothetical protein, conserved
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— OG7
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0064120
hypothetical protein, conserved
— OG7
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0089090
hypothetical protein, conserved
— OG7
TcYC6_0009740
CHAT domain containing protein, putative
— OG7
TcYC6_0034510
ecotin, putative
— OG7
TcYC6_0063100 ⚠
putative protein transport protein SEC23
— OG7
TcYC6_0081900 ⚠
putative replication factor C, subunit 1
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0040710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0061240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0048180 ⚠
ATPase family associated with various cellula
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.