TcYC6_0031230

poly(A)-specific ribonuclease PARN, putative
Trypanosoma cruzi Y C6 OG6: OG6_102215 OG7: OG7_0005534 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— Both
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— Both
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— Both
TcYC6_0061240 ⚠
hypothetical protein, conserved
— Both
TcYC6_0061260 ⚠
helicase, putative
— Both
TcYC6_0061280 ⚠
helicase, putative
— Both
TcYC6_0061220 ⚠
helicase, putative
— Both
TcYC6_0072920 ⚠
phenylalanyl-tRNA synthetase (beta subunit),
— Both
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0044070 ⚠
Domain of unknown function(DUF2779), putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0079510 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0014560 ⚠
geranylgeranyltransferase type I beta subunit
— OG7
TcYC6_0079500 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcYC6_0054430 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0066650 ⚠
putative tubulin tyrosine ligase
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0091340 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcYC6_0066660 ⚠
hypothetical protein
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0116650 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0070930 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0096210 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— Both
TcYC6_0049230 ⚠
otubain cysteine peptidase, Clan CA, family C
— Both
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— Both
TcYC6_0026340 ⚠
hypothetical protein
— OG6
TcYC6_0017040 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0031670 ⚠
pteridine reductase
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0095370 ⚠
hypothetical protein, conserved
— Both
TcYC6_0085910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0064660 ⚠
hypothetical protein, conserved
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0120270 ⚠
putative Leucine rich repeat
— Both
TcYC6_0125540 ⚠
The ARF-like 2 binding protein BART, putative
— Both
TcYC6_0025540 ⚠
tRNA nucleotidyltransferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.