TcYC6_0072920

phenylalanyl-tRNA synthetase (beta subunit), putative

Trypanosoma cruzi Y C6 OG6: OG6_101233 OG7: OG7_0004252 202 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 202 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0083670 tubulin folding cofactor D, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005548	Both
TcYC6_0089430 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG6 LdBPK_191010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	Both
TcYC6_0023910 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	OG7
TcYC6_0022580 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	OG7
TcYC6_0095250 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	OG7
TcYC6_0015370 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	OG7
TcYC6_0068420 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_230660.1	OG7
TcYC6_0091190 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_240010.1	OG7
TcYC6_0065870 hypothetical protein, conserved	—	OG6 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_191010.1 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_191010.1	Both
TcYC6_0123380 hypothetical protein, conserved	—	OG6 LdBPK_191010.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005548	Both
TcYC6_0017360 ⚠ putative developmentally regulated phosphopro	—	OG6 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_240010.1	Both
TcYC6_0121920 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_230660.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_230660.1	Both
TcYC6_0053470 phenylalanyl-tRNA synthetase alpha chain, put	—	OG6 TCSYLVIO_004213 ↔ TCSYLVIO_005548 OG6 Tb927.11.14120 ↔ Tb927.11.2360 OG7 Tb927.11.14120 ↔ Tb927.11.2360 OG7 TCSYLVIO_004213 ↔ TCSYLVIO_005548	Both
TcYC6_0080930 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_005548 OG6 LdBPK_191010.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005548 +1 more	Both
TcYC6_0095370 hypothetical protein, conserved	—	OG6 LdBPK_191010.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_300580.1	Both
TcYC6_0061220 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_191010.1 OG6 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_191010.1	Both
TcYC6_0061240 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_120255.1 ↔ LdBPK_191010.1 OG6 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_191010.1	Both
TcYC6_0061260 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_191010.1 OG6 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_191010.1	Both
TcYC6_0061280 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_191010.1 OG6 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_191010.1	Both
TcYC6_0031230 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_230660.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_230660.1	Both
TcYC6_0099550 ⚠ lysyl-tRNA synthetase, putative	—	OG6 Tb927.11.2360 ↔ Tb927.8.1600 OG7 Tb927.11.2360 ↔ Tb927.8.1600	Both
TcYC6_0021550 ⚠ hypothetical protein	—	OG7 TCSYLVIO_005548 ↔ TCSYLVIO_005619	OG7
TcYC6_0012030 ⚠ hypothetical protein	—	OG7 LdBPK_120470.1 ↔ LdBPK_191010.1	OG7
TcYC6_0040350 ⚠ PPPDE putative peptidase domain containing pr	—	OG6 LdBPK_191010.1 ↔ LdBPK_240660.1 OG7 LdBPK_191010.1 ↔ LdBPK_240660.1	Both
TcYC6_0110770 aspartyl aminopeptidase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_292470.1 OG7 LdBPK_191010.1 ↔ LdBPK_292470.1	Both
TcYC6_0072080 hypothetical protein, conserved	—	OG6 LdBPK_191010.1 ↔ LdBPK_331980.1 OG7 LdBPK_191010.1 ↔ LdBPK_331980.1	Both
TcYC6_0073500 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_005548	OG7
TcYC6_0068480 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_005548	OG7
TcYC6_0040300 ⚠ PPPDE putative peptidase domain containing pr	—	OG6 LdBPK_191010.1 ↔ LdBPK_240660.1 OG7 LdBPK_191010.1 ↔ LdBPK_240660.1	Both
TcYC6_0100340 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_005548	OG7
TcYC6_0111530 ⚠ 6-phosphofructo-2-kinase 1	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_005548	OG7
TcYC6_0080710 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_005548	OG7
TcYC6_0121960 ⚠ ubiquitin-protein ligase, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_191010.1	OG7
TcYC6_0092100 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_161180.1 ↔ LdBPK_191010.1	OG7
TcYC6_0099570 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_191010.1	OG7
TcYC6_0095890 ⚠ ubiquitin-protein ligase	—	OG7 LdBPK_161180.1 ↔ LdBPK_191010.1	OG7
TcYC6_0111330 ⚠ radial spoke protein RSP10, putative	—	OG7 TCSYLVIO_001987 ↔ TCSYLVIO_005548	OG7
TcYC6_0072780 ⚠ aminopeptidase, putative,metallo-peptidase, C	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005548	OG7
TcYC6_0043360 PUB domain containing protein, putative	—	OG6 LdBPK_110920.1 ↔ LdBPK_191010.1 OG7 LdBPK_110920.1 ↔ LdBPK_191010.1	Both
TcYC6_0009740 CHAT domain containing protein, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_210240.1 OG7 LdBPK_191010.1 ↔ LdBPK_210240.1	Both
TcYC6_0071320 hypothetical protein, conserved	—	OG6 LdBPK_191010.1 ↔ LdBPK_354870.1 OG7 LdBPK_191010.1 ↔ LdBPK_354870.1	Both
TcYC6_0072770 Unc104-like kinesin	—	OG6 LdBPK_191010.1 ↔ LdBPK_332690.1	OG6
TcYC6_0009900 vacuolar protein sorting-associated protein 3	—	OG6 LdBPK_191010.1 ↔ LdBPK_210530.1 OG7 LdBPK_191010.1 ↔ LdBPK_210530.1	Both
TcYC6_0034770 ribonucleoprotein p18, mitochondrial precurso	—	OG6 TCSYLVIO_002426 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_005548	Both
TcYC6_0060680 ⚠ Centrosomal protein of 164 kDa, putative	—	OG6 LdBPK_120470.1 ↔ LdBPK_191010.1 OG7 LdBPK_120470.1 ↔ LdBPK_191010.1	Both
TcYC6_0022010 hypothetical protein, conserved	—	OG6 LdBPK_191010.1 ↔ LdBPK_212030.1 OG7 LdBPK_191010.1 ↔ LdBPK_212030.1	Both
TcYC6_0080950 clathrin coat assembly protein, putative	—	OG6 TCSYLVIO_001569 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_001569 ↔ TCSYLVIO_005548	Both
TcYC6_0112280 nuclear cap binding complex subunit CBP110, p	—	OG6 TCSYLVIO_004536 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_004536 ↔ TCSYLVIO_005548	Both
TcYC6_0046920 vacuolar ATP synthase subunit d	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_005548	Both
TcYC6_0044260 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005548	Both

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