TcYC6_0111640

putative ATP-dependent DEAD/H RNA helicase
Trypanosoma cruzi Y C6 OG6: OG6_105684 OG7: OG7_0002665 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0005570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
TcYC6_0051840 ⚠
Importin subunit beta-4, putative
— OG7
TcYC6_0049610 ⚠
hypothetical protein
— OG7
TcYC6_0080650 ⚠
elongation factor 2
— OG7
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG7
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0016510 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0008800 ⚠
methyltransferase, putative
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0125830 ⚠
proteasome subunit beta type-5, putative
— OG7
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0022090 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcYC6_0125780 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcYC6_0019050 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcYC6_0121250 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TcYC6_0068380 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0091520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068780 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcYC6_0124360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0091340 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcYC6_0175380 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0053860 ⚠
Outer row dynein-assembly protein 7
— OG7
TcYC6_0124390 ⚠
putative metallo-peptidase, Clan MC, Family M
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0107480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0034510 ⚠
ecotin, putative
— OG7
TcYC6_0122700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0126250 ⚠
PIF1 helicase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.