TcYC6_0031180

ubiquitin-activating enzyme E1, putative
Trypanosoma cruzi Y C6 OG6: OG6_100444 OG7: OG7_0003530 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— Both
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0047950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcYC6_0093680 ⚠
Beta-lactamase superfamily domain containing
— Both
TcYC6_0030520 ⚠
hypothetical protein
— Both
TcYC6_0119730 ⚠
metallo-peptidase, Clan MG, Family M24, putat
— Both
TcYC6_0102010 ⚠
CMGC/MAPK protein kinase, putative
— Both
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
TcYC6_0046970 ⚠
proteasome activator protein pa26, putative
— Both
TcYC6_0124300 ⚠
hydrogenase, putative
— Both
TcYC6_0063970 ⚠
oxidoreductase, putative
— OG7
TcYC6_0063850 ⚠
oxidoreductase, putative
— OG7
TcYC6_0049610 ⚠
hypothetical protein
— OG7
TcYC6_0080650 ⚠
elongation factor 2
— OG7
TcYC6_0066640 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcYC6_0054440 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0123530 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0074260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0042360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0109530 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056280 ⚠
putative regulator of chromosome condensation
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0093980 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097290 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0111640 ⚠
putative ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0175230 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0053230 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0057750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0091260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0086170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0055270 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0028450 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcYC6_0010370 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0052650 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.