TcYC6_0102010

CMGC/MAPK protein kinase, putative
Trypanosoma cruzi Y C6 OG6: OG6_156867 OG7: OG7_0051037 31 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 31 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0002740 ⚠
ABC transporter, putative
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0029650 ⚠
ABC transporter, putative
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0024170 ⚠
ABC transporter, putative
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0004150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0000760 ⚠
serine/threonine-protein kinase NAK, putative
— OG7
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0101960
ubiquitin-like protein, putative
— OG6
TcYC6_0080650 ⚠
elongation factor 2
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcYC6_0046970
proteasome activator protein pa26, putative
— Both
TcYC6_0103830
peptidase, putative
— Both
TcYC6_0027700 ⚠
NAK family pseudokinase, putative
— Both
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— Both
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— Both
TcYC6_0054390 ⚠
Met-10+ like-protein, putative
— Both
TcYC6_0018590
glutathione synthetase, putative
— Both
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
TcYC6_0100420
splicing factor TSR1, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.