TcYC6_0018590

glutathione synthetase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101596 OG7: OG7_0006266 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0109720
hypothetical protein
— Both
TcYC6_0048020
Probable N6-adenine methyltransferase, putati
— Both
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0102110
hypothetical protein, conserved
— OG7
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcYC6_0051840 ⚠
Importin subunit beta-4, putative
— OG7
TcYC6_0102010
CMGC/MAPK protein kinase, putative
— Both
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0124260
hypothetical protein, conserved
— Both
TcYC6_0103280
hypothetical protein, conserved
— Both
TcYC6_0110700
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0016550
RWD domain-containing protein
— Both
TcYC6_0078090 ⚠
serine peptidase , putative
— Both
TcYC6_0070930 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— Both
TcYC6_0046970
proteasome activator protein pa26, putative
— Both
TcYC6_0000830 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcYC6_0030720
hypothetical protein, conserved
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0021560 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0080730 ⚠
cap guanine-N7 methyltransferase
— OG7
TcYC6_0004150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0024170 ⚠
ABC transporter, putative
— OG7
TcYC6_0029650 ⚠
ABC transporter, putative
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcYC6_0002740 ⚠
ABC transporter, putative
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0084510
Dyggve-Melchior-Clausen syndrome protein, put
— Both
TcYC6_0054390 ⚠
Met-10+ like-protein, putative
— Both
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcYC6_0109670
Cell growth-regulating nucleolar protein, put
— Both
TcYC6_0096210 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— Both
TcYC6_0097480 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
TcYC6_0077860 ⚠
serine peptidase , putative
— Both
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— Both
TcYC6_0092230 ⚠
cap guanylyltransferase-methyltransferase 1
— Both
TcYC6_0100420
splicing factor TSR1, putative
— Both
TcYC6_0049610 ⚠
hypothetical protein
— Both
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcYC6_0012490 ⚠
dipeptidyl-peptidase, putative
— Both
TcYC6_0012090 ⚠
dipeptidyl-peptidase, putative
— Both
TcYC6_0047750
peptidase t, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.