TcYC6_0049610

hypothetical protein
Trypanosoma cruzi Y C6 OG6: OG6_102877 OG7: OG7_0003452 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0111640 ⚠
putative ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcYC6_0124360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0114330 ⚠
polyprenyl synthase, putative
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0080730 ⚠
cap guanine-N7 methyltransferase
— OG7
TcYC6_0091520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0068780 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG7
TcYC6_0102110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021560 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0109950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcYC6_0008800 ⚠
methyltransferase, putative
— OG7
TcYC6_0118160 ⚠
GTP-binding nuclear protein rtb2, putative
— OG7
TcYC6_0016510 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— OG7
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0080650 ⚠
elongation factor 2
— OG7
TcYC6_0089960 ⚠
Carboxypeptidase-like protein
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0124390 ⚠
putative metallo-peptidase, Clan MC, Family M
— OG7
TcYC6_0068400 ⚠
Importin 1
— OG7
TcYC6_0072570 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
TcYC6_0095730 ⚠
hypothetical protein, conserved
— Both
TcYC6_0093290 ⚠
hypothetical protein, conserved
— Both
TcYC6_0088060 ⚠
hypothetical protein, conserved
— Both
TcYC6_0077050 ⚠
serine peptidase , putative
— Both
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— Both
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.