TcYC6_0095730

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_113914 OG7: OG7_0021257 129 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 129 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0091590
hypothetical protein
— Both
TcYC6_0045070
hypothetical protein
— Both
TcYC6_0034710 ⚠
RNA pseudouridylate synthase, putative
— Both
TcYC6_0034770
ribonucleoprotein p18, mitochondrial precurso
— Both
TcYC6_0016790
cyclophilin 15, putative
— Both
TcYC6_0115840
PA26 p53-induced protein (sestrin), putative
— Both
TcYC6_0093290
hypothetical protein, conserved
— Both
TcYC6_0083540
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0095370
hypothetical protein, conserved
— Both
TcYC6_0083670
tubulin folding cofactor D, putative
— Both
TcYC6_0016660
conserved protein, unknown function
— Both
TcYC6_0112560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0051880
phosphatidylinositol kinase, putative
— OG7
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0088260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0070640 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0024720 ⚠
putative RNA pseudouridylate synthase protein
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0092200 ⚠
R3H domain containing protein, putative
— OG7
TcYC6_0042140
hypothetical protein, conserved
— OG7
TcYC6_0059600 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0114330
polyprenyl synthase, putative
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.