TcYC6_0092200

R3H domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_103027 OG7: OG7_0005137 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0014560 ⚠
geranylgeranyltransferase type I beta subunit
— OG7
TcYC6_0119300 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0099300 ⚠
STE/STE7 protein kinase, putative
— OG7
TcYC6_0093290 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012030 ⚠
hypothetical protein
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0091340 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0053860 ⚠
Outer row dynein-assembly protein 7
— OG7
TcYC6_0005570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097650 ⚠
replication factor C, subunit 2, putative
— OG7
TcYC6_0048180 ⚠
ATPase family associated with various cellula
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0069360 ⚠
replication factor C, subunit 3, putative
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0068840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104860 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcYC6_0086990 ⚠
hypothetical protein
— OG7
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0095730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0045680 ⚠
TLD, putative
— OG7
TcYC6_0126250 ⚠
PIF1 helicase-like protein
— OG7
TcYC6_0114330 ⚠
polyprenyl synthase, putative
— OG7
TcYC6_0048800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049260 ⚠
zinc-finger protein ZPR1, putative
— OG7
TcYC6_0034510 ⚠
ecotin, putative
— OG7
TcYC6_0119220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0100560 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0107480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104830 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0104800 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.