TcYC6_0113000

FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100299 OG7: OG7_0001020 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcYC6_0080020 ⚠
C21orf2-like protein, putative
— OG7
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcYC6_0005360 ⚠
amidohydrolase, putative
— OG7
TcYC6_0005340 ⚠
amidohydrolase, putative
— OG7
TcYC6_0005350 ⚠
aminoacylase, putative
— OG7
TcYC6_0092200 ⚠
R3H domain containing protein, putative
— OG7
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— OG7
TcYC6_0036970 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcYC6_0059600 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0024720 ⚠
putative RNA pseudouridylate synthase protein
— OG7
TcYC6_0034710 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0075110 ⚠
hypothetical protein
— OG7
TcYC6_0122330 ⚠
flagellum transition zone component, putative
— OG7
TcYC6_0126950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0122250 ⚠
hypothetical protein
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0071020 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— OG7
TcYC6_0122260 ⚠
hypothetical protein
— OG7
TcYC6_0099000 ⚠
putative cyclin
— OG7
TcYC6_0122140 ⚠
flagellum transition zone component, putative
— OG7
TcYC6_0110620 ⚠
leucine-rich repeat-containing protein
— OG7
TcYC6_0123050 ⚠
adenylyl cyclase-associated protein, putative
— OG7
TcYC6_0088160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0101620 ⚠
N-acetyltransferase complex ARD1 subunit
— OG7
TcYC6_0092780 ⚠
Tcc2i18.7
— OG7
TcYC6_0048660 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
TcYC6_0114330 ⚠
polyprenyl synthase, putative
— OG7
TcYC6_0046000 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0048800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049260 ⚠
zinc-finger protein ZPR1, putative
— OG7
TcYC6_0059390 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0120140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049110 ⚠
methyltransferase domain containing protein,
— OG7
TcYC6_0095260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0098400 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcYC6_0106460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088430 ⚠
EAP30/Vps36 family, putative
— OG7
TcYC6_0095730 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.