TcYC6_0110620

leucine-rich repeat-containing protein
Trypanosoma cruzi Y C6 OG6: OG6_104522 OG7: OG7_0009175 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0097620 ⚠
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044200 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcYC6_0044210 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0075310 ⚠
hypothetical protein
— Both
TcYC6_0117610
hypothetical protein, conserved
— OG6
TcYC6_0076330
small nuclear ribonucleoprotein protein, puta
— Both
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0036970
ribonucleoside-diphosphate reductase small ch
— Both
TcYC6_0064250
hypothetical protein, conserved
— Both
TcYC6_0113920 ⚠
protein kinase
— OG6
TcYC6_0083190 ⚠
Calcium/calmodulin-dependent protein kinase k
— Both
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0121410 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
TcYC6_0125080 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0068670 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcYC6_0110800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0046610 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcYC6_0119750 ⚠
mitochondrial import inner membrane transloca
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0068080 ⚠
protein kinase, putative
— Both
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0044720 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0050640 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0057750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0175230 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcYC6_0056280 ⚠
putative regulator of chromosome condensation
— OG7
TcYC6_0016570
cytidine triphosphate synthase, putative
— Both
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0027670
tRNA synthetases class II (A)/Threonyl and Al
— Both
TcYC6_0056110 ⚠
putative adrenodoxin precursor
— Both
TcYC6_0005610
translation initiation factor 2 subunit, puta
— Both
TcYC6_0088430
EAP30/Vps36 family, putative
— Both
TcYC6_0072270
hypothetical protein, conserved
— Both
TcYC6_0123050
adenylyl cyclase-associated protein, putative
— Both
TcYC6_0105150 ⚠
adrenodoxin precursor, putative
— Both
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0123960
hypothetical protein, conserved
— Both
TcYC6_0126950
hypothetical protein, conserved
— Both
TcYC6_0052410
hypothetical protein, conserved
— Both
TcYC6_0052320
Cation efflux family, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.