TcYC6_0091590

hypothetical protein

Trypanosoma cruzi Y C6 OG6: OG6_102146 OG7: OG7_0007449 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0126920 serine peptidase, Clan SC, Family S9B	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007536	Both
TcYC6_0115500 ATP12 chaperone protein, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006163 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006163	Both
TcYC6_0114290 C-terminal motor kinesin	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006065	OG6
TcYC6_0121420 ⚠ beta adaptin, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_004597 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_004597	Both
TcYC6_0072920 phenylalanyl-tRNA synthetase (beta subunit),	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005548	Both
TcYC6_0063050 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_010944	Both
TcYC6_0017360 ⚠ putative developmentally regulated phosphopro	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003690	Both
TcYC6_0123380 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_004736	Both
TcYC6_0050640 ⚠ ubiquitin hydrolase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005374 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005374	Both
TcYC6_0017070 ⚠ putative calpain-like cysteine peptidase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007342	OG6
TcYC6_0007460 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_009198	Both
TcYC6_0047480 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008502	Both
TcYC6_0024530 ⚠ inositol 5-phosphatase 1	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007569 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007569	Both
TcYC6_0061240 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006977	Both
TcYC6_0066100 ⚠ ubiquitin-activating enzyme	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_010542	Both
TcYC6_0073420 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005512 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005512	Both
TcYC6_0069500 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005810	Both
TcYC6_0089450 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_003865 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_003865	Both
TcYC6_0107880 Facilitates chromatin transcription complex s	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_010728	Both
TcYC6_0024850 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007342	OG6
TcYC6_0062380 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007511	Both
TcYC6_0124540 ⚠ heat shock protein 85, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008621 +2 more	Both
TcYC6_0047490 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008502	Both
TcYC6_0065870 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_010560	Both
TcYC6_0062940 hypothetical protein, conserved	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008446 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008446	Both
TcYC6_0088920 Zeta toxin, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_010958	Both
TcYC6_0032520 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007603	Both
TcYC6_0061260 ⚠ helicase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006977	Both
TcYC6_0015540 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_009880	Both
TcYC6_0061280 ⚠ helicase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006977	Both
TcYC6_0124550 ⚠ putative heat shock protein 85	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008621 +2 more	Both
TcYC6_0026330 ⚠ calpain-like cysteine peptidase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007342	OG6
TcYC6_0061220 ⚠ helicase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006977	Both
TcYC6_0046920 vacuolar ATP synthase subunit d	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005104	Both
TcYC6_0053470 phenylalanyl-tRNA synthetase alpha chain, put	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_004213 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_004213	Both
TcYC6_0091400 GRIP domain containing protein, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_003707 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_003707	Both
TcYC6_0026340 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007342	OG6
TcYC6_0017040 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_007342	OG6
TcYC6_0031670 pteridine reductase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008848	Both
TcYC6_0072130 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005619	Both
TcYC6_0047040 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003690 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_008502	Both
TcYC6_0089430 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_003867	Both
TcYC6_0022120 ATP synthase F1 subunit gamma protein, putati	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_009375	Both
TcYC6_0114860 Histone chaperone Rttp106-like, putative	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006113 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006113	Both
TcYC6_0120590 ⚠ putative Leucine rich repeat	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006421 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006421	Both
TcYC6_0120270 ⚠ putative Leucine rich repeat	—	OG6 TCSYLVIO_003690 ↔ TCSYLVIO_006421 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_006421	Both
TcYC6_0043810 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003690 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003690	Both
TcYC6_0080930 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_003690 OG7 TCSYLVIO_003690 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003690	Both
TcYC6_0030660 coronin, putative	—	OG6 TCSYLVIO_000174 ↔ TCSYLVIO_003690 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_003690	Both
TcYC6_0095100 kinesin, putative	—	OG6 TCSYLVIO_003093 ↔ TCSYLVIO_003690	OG6

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