TcYC6_0044600

proteasome beta 3 subunit, putative

Trypanosoma cruzi Y C6 OG6: OG6_101970 OG7: OG7_0007205 41 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 41 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0044220 ⚠ proteasome alpha 7 subunit, putative	—	OG6 LdBPK_110240.1 ↔ LdBPK_280110.1 OG6 Tb927.11.7020 ↔ Tb927.11.7270 OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001736 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcYC6_0125780 ⚠ proteasome subunit alpha type-1, putative	—	OG6 Tb11.v5.0196 ↔ Tb927.11.7270 OG6 Tb927.10.6030 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361670.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004937 +20 more	Both
TcYC6_0061700 ⚠ proteasome beta-1 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_006999 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 +6 more	Both
TcYC6_0019050 ⚠ proteasome alpha 3 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.7.4420 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010341 OG6 LdBPK_140310.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcYC6_0071370 ⚠ proteasome alpha 1 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.9.9670 OG6 LdBPK_280110.1 ↔ LdBPK_354910.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005678 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcYC6_0117350 ⚠ proteasome alpha 7 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.3.780 OG6 LdBPK_270190.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7020 ↔ Tb927.11.7270 OG7 Tb927.10.230 ↔ Tb927.11.7270 +18 more	Both
TcYC6_0022090 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.11.7270 OG6 LdBPK_212200.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7020 ↔ Tb927.11.7270 OG7 Tb927.10.230 ↔ Tb927.11.7270 +18 more	Both
TcYC6_0125830 ⚠ proteasome subunit beta type-5, putative	—	OG6 Tb927.10.6080 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TcYC6_0023180 ⚠ proteasome alpha 2 subunit, putative	—	OG6 Tb927.10.290 ↔ Tb927.11.7270 OG6 LdBPK_212070.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_009369 OG7 Tb927.11.7020 ↔ Tb927.11.7270 +19 more	Both
TcYC6_0070050 ⚠ proteasome beta 2 subunit, putative	—	OG6 LdBPK_280110.1 ↔ LdBPK_353880.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005774 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TcYC6_0041700 proteasome beta 6 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_280110.1 OG7 Tb927.11.7270 ↔ Tb927.7.4790 OG7 LdBPK_060140.1 ↔ LdBPK_280110.1	Both
TcYC6_0080470 proteasome subunit beta type-2, putative	—	OG6 Tb927.10.4710 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_360340.1 OG7 LdBPK_280110.1 ↔ LdBPK_360340.1 OG7 Tb927.10.4710 ↔ Tb927.11.7270	Both
TcYC6_0072160 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcYC6_0049920 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
TcYC6_0003610 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcYC6_0090240 putative ribosomal RNA processing protein 6	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_003804 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_003804	Both
TcYC6_0111640 ⚠ putative ATP-dependent DEAD/H RNA helicase	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	Both
TcYC6_0018410 Cold-shock DNA-binding domain containing prot	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
TcYC6_0065750 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	OG7
TcYC6_0023210 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcYC6_0050130 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcYC6_0103040 ⚠ T-complex protein 1, zeta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcYC6_0070070 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcYC6_0073570 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcYC6_0121250 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TcYC6_0127520 ⚠ ATP-dependent RNA helicase MTR4	—	OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004479	OG7
TcYC6_0123300 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcYC6_0103930 acetyl-CoA carboxylase	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_002772	Both
TcYC6_0112490 eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
TcYC6_0004110 acetyltransferase, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004519 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004519	Both
TcYC6_0065270 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004731	Both
TcYC6_0109730 hypothetical protein, conserved	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004312	Both
TcYC6_0094120 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
TcYC6_0068330 helicase, putative	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001736	OG6
TcYC6_0053320 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcYC6_0030620 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	Both
TcYC6_0050570 ⚠ ATP binding protein-like protein, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001736	Both
TcYC6_0076090 ⚠ Phosducin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001736	Both
TcYC6_0044190 Phosphoenolpyruvate carboxykinase, related	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_001736	Both
TcYC6_0050730 proteasome regulatory non-ATPase subunit 7, p	—	OG6 Tb927.11.16030 ↔ Tb927.11.7270 OG7 Tb927.11.16030 ↔ Tb927.11.7270	Both
TcYC6_0091650 proteasome beta 7 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.4.430 OG7 Tb927.11.7270 ↔ Tb927.4.430	Both