TcYC6_0018410

Cold-shock DNA-binding domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_147036 OG7: OG7_0042945 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0103330 ⚠
hypothetical protein
— OG7
TcYC6_0101780 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— Both
TcYC6_0061700 ⚠
proteasome beta-1 subunit, putative
— Both
TcYC6_0057130
Ribosome production factor 2-like protein
— Both
TcYC6_0050130 ⚠
chaperonin alpha subunit, putative
— Both
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0013090
oxidoreductase-like protein, putative
— Both
TcYC6_0103060 ⚠
mitochondrial DNA polymerase I protein D, put
— Both
TcYC6_0044600
proteasome beta 3 subunit, putative
— Both
TcYC6_0045820
lipin, putative
— Both
TcYC6_0068330
helicase, putative
— OG6
TcYC6_0076350 ⚠
hypothetical protein, conserved
— Both
TcYC6_0071370 ⚠
proteasome alpha 1 subunit, putative
— Both
TcYC6_0125780 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcYC6_0016690 ⚠
vesicular-fusion protein nsf, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0057760 ⚠
RNA editing complex protein MP57, putative
— OG7
TcYC6_0013250 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcYC6_0018540 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcYC6_0125830 ⚠
proteasome subunit beta type-5, putative
— OG7
TcYC6_0117350 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcYC6_0019050 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcYC6_0112490
eukaryotic translation initiation factor 5, p
— Both
TcYC6_0022090 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0121250 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— Both
TcYC6_0031280
hypothetical protein, conserved
— Both
TcYC6_0090240
putative ribosomal RNA processing protein 6
— Both
TcYC6_0050570 ⚠
ATP binding protein-like protein, putative
— Both
TcYC6_0076090 ⚠
Phosducin, putative
— Both
TcYC6_0044190
Phosphoenolpyruvate carboxykinase, related
— Both
TcYC6_0111640 ⚠
putative ATP-dependent DEAD/H RNA helicase
— Both
TcYC6_0098390
putative kinesin
— OG6
TcYC6_0082720
hypothetical protein
— Both
TcYC6_0084700
endo-beta-N-acetylglucosaminidase, putative
— Both
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0023180 ⚠
proteasome alpha 2 subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.