TcYC6_0013250

kinetoplast poly(A) polymerase 1
Trypanosoma cruzi Y C6 OG6: OG6_139718 OG7: OG7_0019075 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0022090 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcYC6_0125780 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcYC6_0019050 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcYC6_0117350 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcYC6_0071370 ⚠
proteasome alpha 1 subunit, putative
— OG7
TcYC6_0093760 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079690 ⚠
RNA editing complex protein MP61, putative
— OG7
TcYC6_0031280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084700 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcYC6_0057130 ⚠
Ribosome production factor 2-like protein
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0080650 ⚠
elongation factor 2
— OG7
TcYC6_0077860 ⚠
serine peptidase , putative
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077050 ⚠
serine peptidase , putative
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0078090 ⚠
serine peptidase , putative
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0000830 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0013440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068250 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
TcYC6_0067670 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
TcYC6_0013090 ⚠
oxidoreductase-like protein, putative
— OG7
TcYC6_0005370 ⚠
mRNA processing protein, putative
— OG7
TcYC6_0050570 ⚠
ATP binding protein-like protein, putative
— OG7
TcYC6_0076090 ⚠
Phosducin, putative
— OG7
TcYC6_0045820 ⚠
lipin, putative
— OG7
TcYC6_0126220 ⚠
DNA mismatch repair protein MSH6, putative
— OG7
TcYC6_0028430 ⚠
mismatch repair protein MSH3
— OG7
TcYC6_0052520 ⚠
coatomer subunit epsilon
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0082720 ⚠
hypothetical protein
— OG7
TcYC6_0116000 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0110770 ⚠
aspartyl aminopeptidase, putative
— OG7
TcYC6_0073980 ⚠
intraflagellar transport protein 88
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0022920 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.