TcYC6_0095240

Eukaryotic translation initiation factor 4E-4
Trypanosoma cruzi Y C6 OG6: OG6_106272 OG7: OG7_0002303 213 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 213 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0085920 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcYC6_0070400 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TcYC6_0119710 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
TcYC6_0012100 ⚠
elongation factor G2-like protein, putative
— OG7
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TcYC6_0112660 ⚠
CS domain containing protein, putative
— OG7
TcYC6_0078640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0093270 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0074780 ⚠
isocitrate dehydrogenase, putative
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0012450 ⚠
Small Surface Antigen
— OG7
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG7
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcYC6_0108170 ⚠
UBX domain-containing protein
— OG7
TcYC6_0088930 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcYC6_0000840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0080140 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcYC6_0079830 ⚠
SNF1-related protein kinase, putative
— OG7
TcYC6_0106350 ⚠
diphthine synthase, putative
— OG7
TcYC6_0112520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0100560 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0111760 ⚠
quinone oxidoreductase, putative
— OG7
TcYC6_0110890 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcYC6_0055560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcYC6_0053370 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcYC6_0044720 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcYC6_0053430 ⚠
Alpha/beta hydrolase family, putative
— OG7
TcYC6_0107700 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— OG7
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0012030 ⚠
hypothetical protein
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0095490 ⚠
pdz domain containing protein, putative
— OG7
TcYC6_0123690 ⚠
Component of motile flagella 12
— OG7
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcYC6_0095910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— OG7
TcYC6_0042220 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcYC6_0012390 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0064930 ⚠
hypothetical protein
— OG7
TcYC6_0055760 ⚠
hypothetical protein, conserved
— OG7
Page 1 of 5
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.