TcYC6_0124680

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_148303 OG7: OG7_0042993 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0013090
oxidoreductase-like protein, putative
— Both
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— Both
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcYC6_0080770 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcYC6_0069000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0007630
hypothetical protein, conserved
— Both
TcYC6_0103230
hypothetical protein, conserved
— Both
TcYC6_0096590 ⚠
pseudouridine synthase A-like protein, putati
— Both
TcYC6_0028290 ⚠
ubiquitin hydrolase
— Both
TcYC6_0057350
hypothetical protein, conserved
— Both
TcYC6_0076360
cdc2-related kinase 9
— OG6
TcYC6_0049770 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0077570
hypothetical protein, conserved
— Both
TcYC6_0048030
Kinetochore interacting protein 5
— OG7
TcYC6_0112560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0086200
hypothetical protein, conserved
— OG7
TcYC6_0015620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012460 ⚠
leucine rich repeat
— OG7
TcYC6_0081220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077600 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0041650
hypothetical protein, conserved
— OG7
TcYC6_0071910
isopentenyl-diphosphate delta-isomerase (type
— Both
TcYC6_0082160
hypothetical protein, conserved
— Both
TcYC6_0114880
Hsp70 protein, putative
— Both
TcYC6_0050830
hypothetical protein, conserved
— Both
TcYC6_0028640
putative glutamate dehydrogenase
— Both
TcYC6_0097580
hypothetical protein, conserved
— Both
TcYC6_0113140
class 3 lipase
— OG6
TcYC6_0089910
hypothetical protein, conserved
— Both
TcYC6_0114430 ⚠
fibrillarin, putative
— Both
TcYC6_0127460 ⚠
fibrillarin, putative
— Both
TcYC6_0097340
SET domain containing protein, putative
— Both
TcYC6_0023240
Domain of unknown function (DUF4042), putativ
— Both
TcYC6_0024550
putative cAMP-specific phosphodiesterase
— Both
TcYC6_0022570
Aminoacyl-tRNA editing domain containing prot
— Both
TcYC6_0005860
vacuolar protein sorting-associated protein-l
— Both
TcYC6_0006410
vacuolar protein sorting-associated protein-l
— Both
TcYC6_0126040
Ribosomal protein S5, C-terminal domain conta
— Both
TcYC6_0052930
G5-interacting protein, putative
— Both
TcYC6_0091570
putative Unc104-like kinesin
— OG6
TcYC6_0123380
hypothetical protein, conserved
— OG6
TcYC6_0080720
PUB domain containing protein, putative
— Both
TcYC6_0077590 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.