TcYC6_0006410

vacuolar protein sorting-associated protein-like, putative
Trypanosoma cruzi Y C6 OG6: OG6_101403 OG7: OG7_0005528 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0091570
putative Unc104-like kinesin
— OG6
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
TcYC6_0112560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0057350
hypothetical protein, conserved
— Both
TcYC6_0071910
isopentenyl-diphosphate delta-isomerase (type
— Both
TcYC6_0096590 ⚠
pseudouridine synthase A-like protein, putati
— Both
TcYC6_0009900
vacuolar protein sorting-associated protein 3
— Both
TcYC6_0082160
hypothetical protein, conserved
— Both
TcYC6_0124680
hypothetical protein, conserved
— Both
TcYC6_0005860
vacuolar protein sorting-associated protein-l
— Both
TcYC6_0023240
Domain of unknown function (DUF4042), putativ
— Both
TcYC6_0097340
SET domain containing protein, putative
— Both
TcYC6_0089910
hypothetical protein, conserved
— Both
TcYC6_0126040
Ribosomal protein S5, C-terminal domain conta
— Both
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.