TcYC6_0025040

spermidine synthase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100634 OG7: OG7_0003460 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0112720 ⚠
malate dehydrogenase, putative
— Both
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0112730 ⚠
malate dehydrogenase
— OG7
TcYC6_0175560 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0044440 ⚠
serine sulfhydrylase
— Both
TcYC6_0175670 ⚠
hypothetical protein
— Both
TcYC6_0044890 ⚠
serine sulfhydrylase
— Both
TcYC6_0046320 ⚠
serine sulfhydrylase
— Both
TcYC6_0044900 ⚠
serine sulfhydrylase
— Both
TcYC6_0044870 ⚠
serine sulfhydrylase
— Both
TcYC6_0128170 ⚠
serine sulfhydrylase
— Both
TcYC6_0006570 ⚠
cysteine synthase, putative
— OG6
TcYC6_0012470 ⚠
ribose 5-phosphate isomerase, putative
— Both
TcYC6_0121550 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0106870 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcYC6_0014130 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
TcYC6_0044910 ⚠
serine sulfhydrylase
— Both
TcYC6_0108140 ⚠
FHA domain containing protein, putative
— OG7
TcYC6_0121630 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0101180 ⚠
Metallopeptidase family M24, putative
— OG7
TcYC6_0094150 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcYC6_0034510 ⚠
ecotin, putative
— OG7
TcYC6_0084140 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcYC6_0120660 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0077360 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0120330 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0077370 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0031400 ⚠
trypanothione synthetase, putative
— OG7
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcYC6_0120630 ⚠
AGC essential kinase 1
— OG6
TcYC6_0076460 ⚠
trypanothione synthetase
— Both
TcYC6_0057490 ⚠
hypothetical protein, conserved
— Both
TcYC6_0087960 ⚠
uracil phosphoribosyltransferase, putative
— Both
TcYC6_0111240 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
TcYC6_0053370 ⚠
ubiquitin-conjugating enzyme E2, putative
— Both
TcYC6_0127970 ⚠
deoxyuridine triphosphatase, putative
— Both
TcYC6_0046120 ⚠
deoxyuridine triphosphatase, putative
— Both
TcYC6_0011340 ⚠
cytosolic malate dehydrogenase, putative
— Both
TcYC6_0058320 ⚠
asparagine synthetase a, putative
— Both
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— Both
TcYC6_0045450 ⚠
Nuclear Dbf2-related kinase
— OG6
TcYC6_0045560 ⚠
deoxyribose-phosphate aldolase, putative
— Both
TcYC6_0114380 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
TcYC6_0096260 ⚠
pyridoxal kinase, putative
— Both
TcYC6_0093060 ⚠
peptidyl-prolyl cis-trans isomerase
— OG6
TcYC6_0072740 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
TcYC6_0021830 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
TcYC6_0099360 ⚠
protein phosphatase 2A, regulatory subunit B,
— Both
TcYC6_0084390 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcYC6_0084380 ⚠
fatty acyl CoA synthetase 2, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.