TcYC6_0011340

cytosolic malate dehydrogenase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101066 OG7: OG7_0004490 31 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 31 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0044440 ⚠
serine sulfhydrylase
— Both
TcYC6_0120330 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0031400 ⚠
trypanothione synthetase, putative
— OG7
TcYC6_0077370 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0077360 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0120660 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0112730 ⚠
malate dehydrogenase
— OG7
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0121550
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0006570 ⚠
cysteine synthase, putative
— OG6
TcYC6_0128170 ⚠
serine sulfhydrylase
— Both
TcYC6_0044870 ⚠
serine sulfhydrylase
— Both
TcYC6_0044900 ⚠
serine sulfhydrylase
— Both
TcYC6_0046320 ⚠
serine sulfhydrylase
— Both
TcYC6_0044890 ⚠
serine sulfhydrylase
— Both
TcYC6_0175670 ⚠
hypothetical protein
— Both
TcYC6_0111240
inosine-adenosine-guanosine-nucleosidehydrola
— Both
TcYC6_0044910 ⚠
serine sulfhydrylase
— Both
TcYC6_0044880 ⚠
serine sulfhydrylase
— Both
TcYC6_0083700
transketolase, putative
— Both
TcYC6_0112720 ⚠
malate dehydrogenase, putative
— Both
TcYC6_0096260
pyridoxal kinase, putative
— Both
TcYC6_0076460 ⚠
trypanothione synthetase
— Both
TcYC6_0046120 ⚠
deoxyuridine triphosphatase, putative
— Both
TcYC6_0024870 ⚠
spermidine synthase, putative
— Both
TcYC6_0025040 ⚠
spermidine synthase, putative
— Both
TcYC6_0019520
threonine synthase, putative
— Both
TcYC6_0058320
asparagine synthetase a, putative
— Both
TcYC6_0127970 ⚠
deoxyuridine triphosphatase, putative
— Both
TcYC6_0036970
ribonucleoside-diphosphate reductase small ch
— Both
TcYC6_0064420
nucleoside phosphorylase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.