TcYC6_0098810

DNA ligase I, putative
Trypanosoma cruzi Y C6 OG6: OG6_100906 OG7: OG7_0002598 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0088140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— Both
TcYC6_0047950 ⚠
hypothetical protein, conserved
— Both
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0111560
Ubiquitin-like domain containing protein, put
— Both
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0097570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0097500 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0093770 ⚠
translation initiation factor IF-2, putative
— Both
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— Both
TcYC6_0000480
casein kinase II, alpha chain, putative
— OG6
TcYC6_0094080
alanyl-tRNA synthetase, putative
— Both
TcYC6_0098450
S-adenosylmethionine decarboxylase proenzyme,
— Both
TcYC6_0014120
phosphonopyruvate decarboxylase, putative
— Both
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcYC6_0012590
Replication factor A protein 1
— Both
TcYC6_0093680 ⚠
Beta-lactamase superfamily domain containing
— Both
TcYC6_0030520 ⚠
hypothetical protein
— Both
TcYC6_0000250
Gar1/Naf1 RNA binding region, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0042390
hypothetical protein, conserved
— Both
TcYC6_0030310
hypothetical protein, conserved
— Both
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— OG7
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0040620 ⚠
cytochrome b5, putative
— OG7
TcYC6_0109080 ⚠
cytochrome b5, putative
— OG7
TcYC6_0058570 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcYC6_0049170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043870 ⚠
cytochrome b5
— OG7
TcYC6_0063970 ⚠
oxidoreductase, putative
— OG7
TcYC6_0063850 ⚠
oxidoreductase, putative
— OG7
TcYC6_0086170
hypothetical protein, conserved
— OG7
TcYC6_0063740 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0066660 ⚠
hypothetical protein
— OG7
TcYC6_0063730 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0063720 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0066650 ⚠
putative tubulin tyrosine ligase
— OG7
TcYC6_0054430 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0125080 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0029650 ⚠
ABC transporter, putative
— OG7
TcYC6_0068670 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcYC6_0110800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.