TcYC6_0000480

casein kinase II, alpha chain, putative
Trypanosoma cruzi Y C6 OG6: OG6_128066 OG7: OG7_0000396 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0030520 ⚠
hypothetical protein
— OG6
TcYC6_0089900
Methyltransferase domain/Methyltransferase in
— OG6
TcYC6_0089340
ATP-dependent RNA helicase, putative
— OG6
TcYC6_0011950 ⚠
MRP protein, putative
— OG6
TcYC6_0095950
p22 protein precursor, putative
— OG6
TcYC6_0012590
Replication factor A protein 1
— OG6
TcYC6_0125270
Protein prenyltransferase alpha subunit repea
— OG6
TcYC6_0098420
homoserine kinase
— OG6
TcYC6_0098810
DNA ligase I, putative
— OG6
TcYC6_0111560
Ubiquitin-like domain containing protein, put
— OG6
TcYC6_0102710
Thiamin pyrophosphokinase, vitamin B1 binding
— OG6
TcYC6_0058780 ⚠
nucleotide-binding protein, putative
— OG6
TcYC6_0000830 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG6
TcYC6_0106020
dihydrouridine synthase (Dus), putative
— OG6
TcYC6_0016680
tubulin-tyrosine ligase, putative
— OG6
TcYC6_0068520
hypothetical protein, conserved
— OG6
TcYC6_0042280
Vta1 like, putative
— OG6
TcYC6_0124300
hydrogenase, putative
— OG6
TcYC6_0028150
general transcription factor IIB
— OG6
TcYC6_0016670
Tubulin/FtsZ family, putative
— OG6
TcYC6_0078090 ⚠
serine peptidase , putative
— OG6
TcYC6_0012440
D123, putative
— OG6
TcYC6_0089960
Carboxypeptidase-like protein
— OG6
TcYC6_0078690
cytosolic nonspecific dipeptidase, putative
— OG6
TcYC6_0116500
hypothetical protein, conserved
— OG6
TcYC6_0005780
Casein kinase II subunit beta, putative
— OG6
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG6
TcYC6_0077860 ⚠
serine peptidase , putative
— OG6
TcYC6_0088960
Regulator of chromosome condensation (RCC1) r
— OG6
TcYC6_0077690
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG6
TcYC6_0074200
XRN 5'-3' exonuclease N-terminus, putative
— OG6
TcYC6_0099210
pitrilysin-like metalloprotease, putative
— OG6
TcYC6_0069370
hypothetical protein
— OG6
TcYC6_0096900
hypothetical protein
— OG6
TcYC6_0066550 ⚠
aspartate carbamoyltransferase, putative
— OG6
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— OG6
TcYC6_0119810
translation elongation factor EF-2, putative
— OG6
TcYC6_0095330
N-acetyltransferase B complex (NatB) non cata
— OG6
TcYC6_0115130
13 kDa deflagellation-inducible protein, puta
— OG6
TcYC6_0067770
Casein kinase II
— OG6
TcYC6_0093680 ⚠
Beta-lactamase superfamily domain containing
— OG6
TcYC6_0057490
hypothetical protein, conserved
— OG6
TcYC6_0045280
mercaptopyruvate sulfurtransferase, putative
— OG6
TcYC6_0077050 ⚠
serine peptidase , putative
— OG6
TcYC6_0088060
hypothetical protein, conserved
— OG6
TcYC6_0022890 ⚠
nucleotide-binding protein, putative
— OG6
TcYC6_0054550 ⚠
aspartate carbamoyltransferase, putative
— OG6
TcYC6_0022540
Programmed cell death protein 2, C-terminal p
— OG6
TcYC6_0015520
hypothetical protein, conserved
— OG6
TcYC6_0091370
ubiquitin hydrolase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.