TcYC6_0086410

kynureninase, putative
Trypanosoma cruzi Y C6 OG6: OG6_103826 OG7: OG7_0008550 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0060390 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0101200
U-box domain containing protein, putative
— Both
TcYC6_0042400
methylthioadenosine phosphorylase, putative
— Both
TcYC6_0043620
anion-transporting ATPase-like, putative
— Both
TcYC6_0044060
hypothetical protein, conserved
— Both
TcYC6_0101340
Uncharacterized ACR, COG1678, putative
— Both
TcYC6_0068430
metallo-peptidase, Clan MG, Family M24, putat
— Both
TcYC6_0057690
Protein of unknown function (DUF525), putativ
— Both
TcYC6_0060380 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0050610
Nucleoside diphosphate kinase 1
— Both
TcYC6_0097130
NUDIX hydrolase domain-like domain-containing
— Both
TcYC6_0077270
hypothetical protein
— Both
TcYC6_0054550 ⚠
aspartate carbamoyltransferase, putative
— Both
TcYC6_0175630
trypanothione reductase, putative
— Both
TcYC6_0066550 ⚠
aspartate carbamoyltransferase, putative
— Both
TcYC6_0115670
aconitase, putative
— Both
TcYC6_0081110
hypothetical protein, conserved
— Both
TcYC6_0068380
hypothetical protein, conserved
— Both
TcYC6_0014120
phosphonopyruvate decarboxylase, putative
— Both
TcYC6_0076700 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcYC6_0017390
cytidine triphosphate synthase, putative
— Both
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0116650 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcYC6_0090760 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0073300 ⚠
choline kinase
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0071890 ⚠
ribosome-interacting GTPase 2, putative
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0102100 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0062350 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcYC6_0049230
otubain cysteine peptidase, Clan CA, family C
— Both
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcYC6_0115870
citrate synthase, putative
— Both
TcYC6_0110480
C-8 sterol isomerase, putative
— Both
TcYC6_0089380
twinfilin
— Both
TcYC6_0099210
pitrilysin-like metalloprotease, putative
— Both
TcYC6_0052410
hypothetical protein, conserved
— Both
TcYC6_0119370
hypothetical protein, conserved
— Both
TcYC6_0052550
NAD+ synthase, putative
— Both
TcYC6_0069150
hypothetical protein, conserved
— Both
TcYC6_0080580
hypothetical protein, conserved
— Both
TcYC6_0126620 ⚠
developmentally regulated GTP-binding protein
— Both
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcYC6_0062480 ⚠
putative choline/ethanolamine kinase
— Both
TcYC6_0062450 ⚠
putative choline/ethanolamine kinase
— Both
TcYC6_0072020
Tcc1i14-2.7
— Both
TcYC6_0074780 ⚠
isocitrate dehydrogenase, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.