TcYC6_0000520

ubiquitin-conjugating enzyme E2, putative
Trypanosoma cruzi Y C6 OG6: OG6_101514 OG7: OG7_0006107 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0062220 ⚠
thioredoxin-like protein, putative
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0086190 ⚠
protein kinase-like protein, putative
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0074910 ⚠
protein kinase
— OG7
TcYC6_0083020 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0030990 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0175660 ⚠
monothiol glutaredoxin, putative
— OG7
TcYC6_0052360
rab11B GTPase, putative
— OG6
TcYC6_0085450 ⚠
monothiol glutaredoxin, putative
— Both
TcYC6_0047940
cytidine deaminase-like protein
— Both
TcYC6_0040260
hypothetical protein, conserved
— OG6
TcYC6_0077680 ⚠
ras-related protein Rab21, putative
— OG6
TcYC6_0109640 ⚠
RNA-binding protein, putative
— Both
TcYC6_0023310 ⚠
ras-related protein Rab21, putative
— OG6
TcYC6_0109660 ⚠
Double RNA binding domain protein 6A
— OG6
TcYC6_0088170
Uncharacterised ACR, YggU family COG1872, put
— Both
TcYC6_0024960
palmitoyl acyltransferase 1, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.