TcYC6_0175660

monothiol glutaredoxin, putative
Trypanosoma cruzi Y C6 OG6: OG6_101660 OG7: OG7_0003454 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0055760 ⚠
hypothetical protein, conserved
— Both
TcYC6_0053220 ⚠
exportin 1, putative
— Both
TcYC6_0007260 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0122380 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcYC6_0067090 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
TcYC6_0112320 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TcYC6_0044570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0076050 ⚠
esterase, putative
— Both
TcYC6_0076180 ⚠
esterase, putative
— Both
TcYC6_0061710 ⚠
PITH domain-containing protein
— Both
TcYC6_0051940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0050280 ⚠
hypothetical protein
— OG7
TcYC6_0076500 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0070700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0030990 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0083020 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0074910 ⚠
protein kinase
— OG7
TcYC6_0000520 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcYC6_0088170 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
TcYC6_0109640 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0086190 ⚠
protein kinase-like protein, putative
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0047940 ⚠
cytidine deaminase-like protein
— OG7
TcYC6_0072350 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0123690 ⚠
Component of motile flagella 12
— Both
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0073580 ⚠
Serine-threonine kinase receptor-associated p
— Both
TcYC6_0031740 ⚠
hypothetical protein, conserved
— Both
TcYC6_0049100 ⚠
Macro domain containing protein, putative
— Both
TcYC6_0062990 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0065990 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TcYC6_0032120 ⚠
hypothetical protein, conserved
— Both
TcYC6_0052370 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0050990 ⚠
superoxide dismutase, putative
— Both
TcYC6_0050860 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0088930 ⚠
pyroglutamyl-peptidase I, putative
— Both
TcYC6_0058160 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TcYC6_0097630 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0091050 ⚠
phosphomannomutase-like protein, putative
— Both
TcYC6_0064930 ⚠
hypothetical protein
— Both
TcYC6_0064940 ⚠
putative GMP synthase
— Both
TcYC6_0098780 ⚠
hypothetical protein, conserved
— Both
TcYC6_0121570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0009250 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.