TcYC6_0062990

Mitogen-activated protein kinase 10, putative
Trypanosoma cruzi Y C6 OG6: OG6_147455 OG7: OG7_0000396 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0051940
hypothetical protein, conserved
— OG6
TcYC6_0051310
hypothetical protein, conserved
— OG6
TcYC6_0112520
hypothetical protein, conserved
— OG6
TcYC6_0019440
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
TcYC6_0115180
mevalonate-diphosphate decarboxylase, putativ
— OG6
TcYC6_0063760
mitogen-activated protein kinase 3, putative
— OG6
TcYC6_0112660 ⚠
CS domain containing protein, putative
— OG6
TcYC6_0070940 ⚠
Co-chaperone protein P23
— OG6
TcYC6_0000840
hypothetical protein, conserved
— OG6
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— OG6
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— OG6
TcYC6_0054200
6-phosphogluconolactonase, putative
— OG6
TcYC6_0108170
UBX domain-containing protein
— OG6
TcYC6_0115350
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
TcYC6_0097640
RNA-binding protein, putative
— OG6
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG6
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG6
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG6
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— OG6
TcYC6_0049770 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcYC6_0049100
Macro domain containing protein, putative
— OG6
TcYC6_0053430
Alpha/beta hydrolase family, putative
— OG6
TcYC6_0096570
epsilon-adaptin, putative
— OG6
TcYC6_0075920
GTP-binding protein, putative
— OG6
TcYC6_0091050
phosphomannomutase-like protein, putative
— OG6
TcYC6_0007710
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG6
TcYC6_0075790 ⚠
TPR-repeat protein, putative
— OG6
TcYC6_0080780 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcYC6_0080140
Elongation factor G1, mitochondrial, putative
— OG6
TcYC6_0109610
carnitine/choline acetyltransferase, putative
— OG6
TcYC6_0110890
Flagellum attachment zone protein 19, putativ
— OG6
TcYC6_0012390
tRNA threonylcarbamoyl adenosine modification
— OG6
TcYC6_0053220
exportin 1, putative
— OG6
TcYC6_0119740
hypothetical protein, conserved
— OG6
TcYC6_0122380
Sucrase/ferredoxin-like, putative
— OG6
TcYC6_0084720
rotamase, putative
— OG6
TcYC6_0125230
nicotinate phosphoribosyltransferase, putativ
— OG6
TcYC6_0112320
Soluble NSF attachment protein, SNAP, putativ
— OG6
TcYC6_0074380
UBA/TS-N domain containing protein, putative
— OG6
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG6
TcYC6_0115010
N-myristoyl transferase, putative
— OG6
TcYC6_0066530 ⚠
dihydroorotase, putative
— OG6
TcYC6_0054750 ⚠
dihydroorotase, putative
— OG6
TcYC6_0107700
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
TcYC6_0116190
UTP-glucose-1-phosphate uridylyltransferase 2
— OG6
TcYC6_0076050 ⚠
esterase, putative
— OG6
TcYC6_0076180 ⚠
esterase, putative
— OG6
TcYC6_0065780
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.