TcYC6_0125570

translation elongation factor 1-beta, putative

Trypanosoma cruzi Y C6 OG6: OG6_101695 OG7: OG7_0003992 53 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 53 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0087400 ⚠ 25 kDa translation elongation factor 1-beta,	—	OG6 LdBPK_340870.1 ↔ LdBPK_361490.1 OG6 Tb927.10.5840 ↔ Tb927.4.3590 OG7 Tb927.10.5840 ↔ Tb927.4.3590 OG7 LdBPK_340870.1 ↔ LdBPK_361490.1	Both
TcYC6_0057050 ⚠ hypothetical protein, conserved	—	OG7 Tb927.10.5840 ↔ Tb927.3.1150	OG7
TcYC6_0075060 ⚠ RNA polymerase I second largest subunit	—	OG6 Tb927.10.5840 ↔ Tb927.11.630 OG7 Tb927.10.5840 ↔ Tb927.11.630	Both
TcYC6_0127510 ⚠ Ribosomal RNA processing protein 41A	—	OG6 Tb927.10.5840 ↔ Tb927.10.7450 OG7 Tb927.10.5840 ↔ Tb927.10.7450	Both
TcYC6_0019570 ⚠ ribosomal RNA processing protein 4, putative	—	OG6 Tb927.10.5840 ↔ Tb927.7.4670 OG7 Tb927.10.5840 ↔ Tb927.7.4670	Both
TcYC6_0049920 ⚠ exosome-associated protein 2, putative	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
TcYC6_0117980 ⚠ hypothetical protein, conserved	—	OG6 Tb927.10.5840 ↔ Tb927.3.1300 OG7 Tb927.10.5840 ↔ Tb927.3.1300	Both
TcYC6_0030370 ⚠ exosome component CSL4, putative	—	OG6 Tb927.10.5840 ↔ Tb927.5.1200 OG7 Tb927.10.5840 ↔ Tb927.5.1200	Both
TcYC6_0118130 ⚠ hypothetical protein, conserved	—	OG6 Tb927.10.5840 ↔ Tb927.3.1150 OG7 Tb927.10.5840 ↔ Tb927.3.1150	Both
TcYC6_0049780 ⚠ hypothetical protein, conserved	—	OG6 Tb927.10.5840 ↔ Tb927.11.16490 OG6 Tb927.11.16490 ↔ Tb927.4.3590 OG7 Tb927.10.5840 ↔ Tb927.11.16490 OG7 Tb927.11.16490 ↔ Tb927.4.3590	Both
TcYC6_0086600 ⚠ hypothetical protein	—	OG6 LdBPK_262390.1 ↔ LdBPK_361490.1 OG6 LdBPK_262390.1 ↔ LdBPK_340870.1 OG7 LdBPK_262390.1 ↔ LdBPK_361490.1 OG7 LdBPK_262390.1 ↔ LdBPK_340870.1	Both
TcYC6_0119230 ⚠ Eukaryotic translation initiation factor 3 su	—	OG6 LdBPK_251670.1 ↔ LdBPK_361490.1 OG6 LdBPK_251670.1 ↔ LdBPK_340870.1 OG7 LdBPK_251670.1 ↔ LdBPK_361490.1 OG7 LdBPK_251670.1 ↔ LdBPK_340870.1	Both
TcYC6_0005580 ⚠ exosome-associated protein 4, putative	—	OG7 Tb927.10.5840 ↔ Tb927.10.7450	OG7
TcYC6_0015370 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.4.2310 ↔ Tb927.4.3590	OG7
TcYC6_0094120 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
TcYC6_0107680 ⚠ DNA-directed RNA polymerase II subunit 2, put	—	OG7 Tb927.10.5840 ↔ Tb927.11.630	OG7
TcYC6_0095250 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.4.2310 ↔ Tb927.4.3590	OG7
TcYC6_0022580 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.4.2310 ↔ Tb927.4.3590	OG7
TcYC6_0023910 ⚠ hypothetical protein, conserved	—	OG7 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.4.2310 ↔ Tb927.4.3590	OG7
TcYC6_0015950 ⚠ DNA-directed RNA polymerase III, putative	—	OG7 Tb927.10.5840 ↔ Tb927.11.630	OG7
TcYC6_0126240 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_342220.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_342220.1	OG7
TcYC6_0099230 ⚠ Sec7 domain containing protein, putative	—	OG7 LdBPK_342220.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_342220.1	OG7
TcYC6_0089660 ⚠ Guanine nucleotide exchange factor in Golgi t	—	OG7 LdBPK_342220.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_342220.1	OG7
TcYC6_0037000 ⚠ hypothetical protein	—	OG7 LdBPK_090810.1 ↔ LdBPK_361490.1 OG7 LdBPK_090810.1 ↔ LdBPK_340870.1	OG7
TcYC6_0028450 ⚠ glutaminyl-tRNA synthetase, putative	—	OG7 LdBPK_303290.1 ↔ LdBPK_361490.1 OG7 LdBPK_303290.1 ↔ LdBPK_340870.1	OG7
TcYC6_0102040 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130700.1 ↔ LdBPK_361490.1 OG7 LdBPK_130700.1 ↔ LdBPK_340870.1	OG7
TcYC6_0046860 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_350610.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_350610.1	OG7
TcYC6_0090600 ⚠ ZFP family member, putative	—	OG6 LdBPK_340870.1 ↔ LdBPK_343240.1 OG6 LdBPK_343240.1 ↔ LdBPK_361490.1 OG7 LdBPK_343240.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_343240.1	Both
TcYC6_0075750 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_272380.1 ↔ LdBPK_361490.1 OG6 LdBPK_272380.1 ↔ LdBPK_340870.1 OG7 LdBPK_272380.1 ↔ LdBPK_361490.1 OG7 LdBPK_272380.1 ↔ LdBPK_340870.1	Both
TcYC6_0091620 ⚠ putative beta prime cop protein	—	OG6 LdBPK_344140.1 ↔ LdBPK_361490.1 OG6 LdBPK_340870.1 ↔ LdBPK_344140.1 OG7 LdBPK_344140.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_344140.1	Both
TcYC6_0017200 ⚠ coatomer beta subunit	—	OG6 LdBPK_201390.1 ↔ LdBPK_361490.1 OG6 LdBPK_201390.1 ↔ LdBPK_340870.1 OG7 LdBPK_201390.1 ↔ LdBPK_361490.1 OG7 LdBPK_201390.1 ↔ LdBPK_340870.1	Both
TcYC6_0011710 ⚠ Coatomer subunit gamma	—	OG6 LdBPK_282820.1 ↔ LdBPK_361490.1 OG6 LdBPK_282820.1 ↔ LdBPK_340870.1 OG7 LdBPK_282820.1 ↔ LdBPK_361490.1 OG7 LdBPK_282820.1 ↔ LdBPK_340870.1	Both
TcYC6_0119190 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_251630.1 ↔ LdBPK_361490.1 OG6 LdBPK_251630.1 ↔ LdBPK_340870.1 OG7 LdBPK_251630.1 ↔ LdBPK_361490.1 OG7 LdBPK_251630.1 ↔ LdBPK_340870.1	Both
TcYC6_0098360 ⚠ eukaryotic translation initiation factor 3 su	—	OG6 LdBPK_303080.1 ↔ LdBPK_361490.1 OG6 LdBPK_303080.1 ↔ LdBPK_340870.1 OG7 LdBPK_303080.1 ↔ LdBPK_361490.1 OG7 LdBPK_303080.1 ↔ LdBPK_340870.1	Both
TcYC6_0017210 ⚠ exosome-associated protein 1, putative	—	OG6 Tb927.1.2580 ↔ Tb927.10.5840 OG7 Tb927.1.2580 ↔ Tb927.10.5840	Both
TcYC6_0089530 ⚠ Sec7 domain containing protein, putative	—	OG6 LdBPK_342220.1 ↔ LdBPK_361490.1 OG6 LdBPK_340870.1 ↔ LdBPK_342220.1 OG7 LdBPK_342220.1 ↔ LdBPK_361490.1 OG7 LdBPK_340870.1 ↔ LdBPK_342220.1	Both
TcYC6_0072470 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_332380.1 ↔ LdBPK_361490.1 OG6 LdBPK_332380.1 ↔ LdBPK_340870.1 OG7 LdBPK_332380.1 ↔ LdBPK_361490.1 OG7 LdBPK_332380.1 ↔ LdBPK_340870.1	Both
TcYC6_0016780 ⚠ transmembrane protein, conserved	—	OG6 LdBPK_200940.1 ↔ LdBPK_361490.1 OG6 LdBPK_200940.1 ↔ LdBPK_340870.1 OG7 LdBPK_200940.1 ↔ LdBPK_361490.1 OG7 LdBPK_200940.1 ↔ LdBPK_340870.1	Both
TcYC6_0121540 ⚠ methyltransferase, putative	—	OG6 Tb927.10.7940 ↔ Tb927.4.3590 OG6 Tb927.10.5840 ↔ Tb927.10.7940 OG7 Tb927.10.5840 ↔ Tb927.10.7940 OG7 Tb927.10.7940 ↔ Tb927.4.3590	Both
TcYC6_0121150 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_340870.1 ↔ LdBPK_367300.1 OG6 LdBPK_361490.1 ↔ LdBPK_367300.1 OG7 LdBPK_340870.1 ↔ LdBPK_367300.1 OG7 LdBPK_361490.1 ↔ LdBPK_367300.1	Both
TcYC6_0024670 ⚠ putative ribosomal RNA processing protein 40	—	OG6 Tb927.10.5840 ↔ Tb927.9.7070 OG7 Tb927.10.5840 ↔ Tb927.9.7070	Both
TcYC6_0123990 ⚠ hypothetical protein	—	OG6 LdBPK_340870.1 ↔ LdBPK_365050.1 OG6 LdBPK_361490.1 ↔ LdBPK_365050.1 OG7 LdBPK_340870.1 ↔ LdBPK_365050.1 OG7 LdBPK_361490.1 ↔ LdBPK_365050.1	Both
TcYC6_0121120 ⚠ eukaryotic translation initiation factor 3 su	—	OG6 LdBPK_340870.1 ↔ LdBPK_367320.1 OG6 LdBPK_361490.1 ↔ LdBPK_367320.1 OG7 LdBPK_340870.1 ↔ LdBPK_367320.1 OG7 LdBPK_361490.1 ↔ LdBPK_367320.1	Both
TcYC6_0089430 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 Tb927.4.2310 ↔ Tb927.4.3590 OG6 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.10.5840 ↔ Tb927.4.2310 OG7 Tb927.4.2310 ↔ Tb927.4.3590	Both
TcYC6_0092980 ⚠ Tripartite attachment complex protein 102	—	OG6 LdBPK_311000.1 ↔ LdBPK_361490.1 OG6 LdBPK_311000.1 ↔ LdBPK_340870.1 OG7 LdBPK_311000.1 ↔ LdBPK_361490.1 OG7 LdBPK_311000.1 ↔ LdBPK_340870.1	Both
TcYC6_0060440 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_120520.1 ↔ LdBPK_361490.1 OG6 LdBPK_120520.1 ↔ LdBPK_340870.1 OG7 LdBPK_120520.1 ↔ LdBPK_361490.1 OG7 LdBPK_120520.1 ↔ LdBPK_340870.1	Both
TcYC6_0164140 ⚠ Mucin-associated surface protein (MASP), subg	—	OG6 LdBPK_141530.1 ↔ LdBPK_361490.1 OG6 LdBPK_141530.1 ↔ LdBPK_340870.1	OG6
TcYC6_0162060 ⚠ Mucin-associated surface protein (MASP), subg	—	OG6 LdBPK_141530.1 ↔ LdBPK_361490.1 OG6 LdBPK_141530.1 ↔ LdBPK_340870.1	OG6
TcYC6_0018180 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_141530.1 ↔ LdBPK_361490.1 OG6 LdBPK_141530.1 ↔ LdBPK_340870.1 OG7 LdBPK_141530.1 ↔ LdBPK_361490.1 OG7 LdBPK_141530.1 ↔ LdBPK_340870.1	Both
TcYC6_0152200 ⚠ mucin TcMUCII, putative	—	OG6 LdBPK_141530.1 ↔ LdBPK_361490.1 OG6 LdBPK_141530.1 ↔ LdBPK_340870.1	OG6

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