TcYC6_0006190

ATP-dependent protease subunit HslV, putative
Trypanosoma cruzi Y C6 OG6: OG6_107204 OG7: OG7_0012703 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0092450 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0049090 ⚠
carnitine O-acetyltransferase
— Both
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— Both
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— Both
TcYC6_0062990
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0064930 ⚠
hypothetical protein
— Both
TcYC6_0064940 ⚠
putative GMP synthase
— Both
TcYC6_0012210
hd phosphohydrolase family protein
— Both
TcYC6_0054780
transaldolase, putative
— Both
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— Both
TcYC6_0091050
phosphomannomutase-like protein, putative
— Both
TcYC6_0088930
pyroglutamyl-peptidase I, putative
— Both
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0095140 ⚠
phosphatase 2C, putative
— OG6
TcYC6_0045720 ⚠
protein phosphatase 2C, putative
— OG6
TcYC6_0120070
succinyl-CoA synthetase alpha subunit, putati
— Both
TcYC6_0115010
N-myristoyl transferase, putative
— Both
TcYC6_0107700
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0045560
deoxyribose-phosphate aldolase, putative
— Both
TcYC6_0044720 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcYC6_0097340
SET domain containing protein, putative
— Both
TcYC6_0027970 ⚠
arginine kinase
— Both
TcYC6_0027890 ⚠
arginine kinase
— Both
TcYC6_0027850 ⚠
arginine kinase
— Both
TcYC6_0045310
hypothetical protein, conserved
— Both
TcYC6_0072920
phenylalanyl-tRNA synthetase (beta subunit),
— Both
TcYC6_0061240 ⚠
hypothetical protein, conserved
— Both
TcYC6_0028640
putative glutamate dehydrogenase
— Both
TcYC6_0061260 ⚠
helicase, putative
— Both
TcYC6_0061280 ⚠
helicase, putative
— Both
TcYC6_0090640 ⚠
ruvB-like DNA helicase, putative
— Both
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0053470
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcYC6_0061220 ⚠
helicase, putative
— Both
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0089760 ⚠
ruvB-like DNA helicase, putative
— Both
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcYC6_0123690
Component of motile flagella 12
— Both
TcYC6_0127570
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
TcYC6_0115110
pyruvate kinase 2, putative
— Both
TcYC6_0050100
dihydrolipoyl dehydrogenase, putative
— Both
TcYC6_0027930 ⚠
arginine kinase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.