TcYC6_0089760

ruvB-like DNA helicase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101635 OG7: OG7_0003574 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0022130 ⚠
centromere/microtubule binding protein cbf5,
— +3 more Both
TcYC6_0090640 ⚠
ruvB-like DNA helicase, putative
— Both
TcYC6_0015540 ⚠
dihydrolipoamide branched chain transacylase,
— Both
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0037010 ⚠
oligopeptidase b
— Both
TcYC6_0175630 ⚠
trypanothione reductase, putative
— Both
TcYC6_0048960 ⚠
sodium/hydrogen exchanger, putative
— Both
TcYC6_0053470 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— Both
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0092450 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0121450 ⚠
prolyl endopeptidase
— OG7
TcYC6_0112730 ⚠
malate dehydrogenase
— OG7
TcYC6_0074850 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0127460 ⚠
fibrillarin, putative
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0006190 ⚠
ATP-dependent protease subunit HslV, putative
— Both
TcYC6_0045980 ⚠
hypothetical protein, conserved
— Both
TcYC6_0049090 ⚠
carnitine O-acetyltransferase
— Both
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— Both
TcYC6_0042220 ⚠
Present in the outer mitochondrial membrane p
— Both
TcYC6_0095910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0084390 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcYC6_0084380 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcYC6_0084400 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcYC6_0084410 ⚠
fatty acyl CoA syntetase 1
— Both
TcYC6_0004020 ⚠
fatty acyl CoA synthetase, putative
— Both
TcYC6_0045310 ⚠
hypothetical protein, conserved
— Both
TcYC6_0061240 ⚠
hypothetical protein, conserved
— Both
TcYC6_0112720 ⚠
malate dehydrogenase, putative
— Both
TcYC6_0028640 ⚠
putative glutamate dehydrogenase
— Both
TcYC6_0061260 ⚠
helicase, putative
— Both
TcYC6_0061280 ⚠
helicase, putative
— Both
TcYC6_0098690 ⚠
MORN repeat-containing protein 1
— Both
TcYC6_0097340 ⚠
SET domain containing protein, putative
— Both
TcYC6_0061220 ⚠
helicase, putative
— Both
TcYC6_0005360 ⚠
amidohydrolase, putative
— Both
TcYC6_0013810 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcYC6_0005340 ⚠
amidohydrolase, putative
— Both
TcYC6_0005350 ⚠
aminoacylase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.