TcYC6_0094040

ATP-dependent DEAD/H RNA helicase, putative
Trypanosoma cruzi Y C6 OG6: OG6_126543 OG7: OG7_0000698 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0069400 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TcYC6_0112580
hypothetical protein, conserved
— OG6
TcYC6_0122950
hypothetical protein, conserved
— OG6
TcYC6_0127000
hypothetical protein, conserved
— OG6
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
TcYC6_0097460
hypothetical protein, conserved
— OG6
TcYC6_0053910
OSM3-like kinesin, putative
— OG6
TcYC6_0058600
putative dynein arm light chain
— OG6
TcYC6_0094770
hypothetical protein, conserved
— OG6
TcYC6_0011620
hypothetical protein, conserved
— OG6
TcYC6_0113430
hypothetical protein, conserved
— OG6
TcYC6_0078830
hypothetical protein, conserved
— OG6
TcYC6_0122820
hypothetical protein, conserved
— OG6
TcYC6_0118170
Putative intraflagellar transport protein A1
— OG6
TcYC6_0109300
kinesin , putative
— OG6
TcYC6_0119510
General negative regulator of transcription s
— OG6
TcYC6_0040230
AAA ATPase, putative
— OG6
TcYC6_0084460
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
TcYC6_0061720
translation initiation factor EIF-2b alpha su
— OG6
TcYC6_0072770
Unc104-like kinesin
— OG6
TcYC6_0093090
proteasome regulatory ATPase subunit 1, putat
— OG6
TcYC6_0067770
Casein kinase II
— OG6
TcYC6_0076120
hypothetical protein, conserved
— OG6
TcYC6_0098800
protein mkt1, putative
— OG6
TcYC6_0079770
hypothetical protein, conserved
— OG6
TcYC6_0052760
Microtubule-binding protein MIP-T3, putative
— OG6
TcYC6_0097780
hypothetical protein, conserved
— OG6
TcYC6_0077570
hypothetical protein, conserved
— OG6
TcYC6_0027980
protein phosphatase 2A regulatory subunit, pu
— OG6
TcYC6_0030670
hypothetical protein, conserved
— OG6
TcYC6_0069390 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TcYC6_0069410 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TcYC6_0114770
putative intraflagellar transport protein 140
— OG6
TcYC6_0121960
ubiquitin-protein ligase, putative
— OG6
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
TcYC6_0111110
Serine/threonine-protein kinase NEK6, putativ
— OG6
TcYC6_0069480
Putative death-receptor fusion protein (DUF24
— OG6
TcYC6_0042470
paraflagellar rod protein, putative
— OG6
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— OG6
TcYC6_0151050 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— OG6
TcYC6_0152760 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0037230
translation-associated element 2, putative
— OG6
TcYC6_0113590
putative Associated kinase of Tb14-3-3
— OG6
TcYC6_0127460 ⚠
fibrillarin, putative
— OG6
TcYC6_0114430 ⚠
fibrillarin, putative
— OG6
TcYC6_0113530
WD domain, G-beta repeat, putative
— OG6
TcYC6_0152900 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0095400
AMP-binding enzyme, putative
— OG6
TcYC6_0099230
Sec7 domain containing protein, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.