TvY486_0100260

deoxyhypusine synthase, putative

Trypanosoma vivax Y486 OG6: OG6_101093 OG7: OG7_0005231 141 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 141 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_1002770 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
TvY486_1003160 ⚠ ABC transporter protein, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TvY486_1106760 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001642 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001642 ↔ TCSYLVIO_004558	Both
TvY486_0702080 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007258	Both
TvY486_0404360 ⚠ calreticulin, putative	—	OG6 TCSYLVIO_002866 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002866 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002866 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002866 ↔ TCSYLVIO_007258	Both
TvY486_0604130 ⚠ T-complex protein 11, putative	—	OG6 TCSYLVIO_003373 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003373 ↔ TCSYLVIO_007258	Both
TvY486_0905830 ⚠ Peroxin 19	—	OG6 TCSYLVIO_005818 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_005818 ↔ TCSYLVIO_007258	Both
TvY486_0601860 ⚠ ubiquitin-protein ligase, putative, (fragment	—	OG6 TCSYLVIO_003155 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_004558	Both
TvY486_0604150 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	Both
TvY486_0604030 ⚠ UV excision repair RAD23 protein, putative, (	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
TvY486_0200730 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
TvY486_0705020 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
TvY486_1113690 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
TvY486_0702380 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
TvY486_0703120 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
TvY486_0700400 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
TvY486_0007940 ⚠ tviv623d01.q1k_22, TPR-repeat protein, putati	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
TvY486_1004460 ⚠ stress-inducible protein STI1-like, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
TvY486_0303980 ⚠ UDP-glucose:glycoprotein glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
TvY486_0600210 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
TvY486_1109070 ⚠ ribonuclease II-like protein, putative, (frag	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
TvY486_0200720 ⚠ Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
TvY486_0706770 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
TvY486_0302140 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TvY486_1107360 ⚠ acidocalcisomal pyrophosphatase, putative, (f	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TvY486_1107390 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TvY486_1107380 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
TvY486_1108060 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
TvY486_0902820 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
TvY486_0401020 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
TvY486_0003610 ⚠ cytochrome b, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TvY486_0302860 ⚠ cytochrome b-domain protein, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TvY486_1114490 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TvY486_1107000 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_007258	OG7
TvY486_0043440 ⚠ hypothetical protein (fragment)	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TvY486_0043450 ⚠ ABC transporter, putative (fragment)	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
TvY486_0700445 ⚠ zinc finger protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0801730 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010724	OG7
TvY486_0905580 ⚠ predicted zinc finger protein, zinc finger pr	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0603580 ⚠ GTPase activator-like protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
TvY486_1004930 ⚠ dihydrouridine synthase domain protein, putat	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
TvY486_0701710 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0700230 ⚠ FYVE zinc finger, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0033450 ⚠ hypothetical protein, conserved in T. vivax (	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010257 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010257	OG7
TvY486_0703750 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0804920 ⚠ tyrosyl/methionyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
TvY486_0024850 ⚠ hypothetical protein, conserved in T. vivax	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
TvY486_0028820 ⚠ hypothetical protein, conserved in T.vivax	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010257 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010257	OG7
TvY486_0402970 ⚠ tRNA-dihydrouridine synthase 4, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
TvY486_0702240 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7

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