TvY486_0401020

cleavage and polyadenylation specificity factor, putative, (fragment)
Trypanosoma vivax Y486 OG6: OG6_101260 OG7: OG7_0002417 143 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 143 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1100100 ⚠
cleavage and polyadenylation specificity fact
— Both
TvY486_0304130 ⚠
hypothetical protein, conserved
— OG7
TvY486_1107120 ⚠
regulator of chromatin condensation, putative
— OG7
TvY486_0041460 ⚠
chromatin binding protein, putative
— OG7
TvY486_0706230 ⚠
BTB/POZ domain/Regulator of chromosome conden
— OG7
TvY486_0806820 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TvY486_0701030 ⚠
regulator of chromosome condensation, putativ
— OG7
TvY486_0701050 ⚠
hypothetical protein, conserved
— OG7
TvY486_1008540 ⚠
rab-like GTPase activating protein, putative
— OG7
TvY486_1008580 ⚠
rab-like GTPase activating protein, putative
— OG7
TvY486_1009060 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TvY486_0602140 ⚠
importin alpha, putative
— OG7
TvY486_0601550 ⚠
histidyl-tRNA synthetase, putative, (fragment
— OG7
TvY486_0702080 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— OG7
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— OG7
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_1012640 ⚠
hypothetical protein, conserved
— OG7
TvY486_0706880 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TvY486_0906450 ⚠
ankyrin repeat protein, putative
— OG7
TvY486_0304430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TvY486_0404540 ⚠
hypothetical protein, conserved
— OG7
TvY486_0806610 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TvY486_0604150 ⚠
DNA ligase I, putative
— OG7
TvY486_0705140 ⚠
ATP-NAD kinase-like protein, (fragment)
— OG7
TvY486_1115300 ⚠
mitochondrial carrier protein, putative
— OG7
TvY486_1100470 ⚠
Regulatory-associated protein of TOR1 (fragme
— OG7
TvY486_0600830 ⚠
hypothetical protein, conserved
— OG7
TvY486_0804320 ⚠
hypothetical protein, conserved
— OG7
TvY486_0201490 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0017240 ⚠
protein kinase
— OG7
TvY486_0601360 ⚠
hypothetical protein, conserved
— OG7
TvY486_0101050 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TvY486_0805850 ⚠
Nucleoporin NUP76
— OG7
TvY486_1004050 ⚠
hypothetical protein, conserved
— OG7
TvY486_0706770 ⚠
hypothetical protein, conserved
— OG7
TvY486_0603870 ⚠
valyl-tRNA synthetase, putative
— OG7
TvY486_0705610 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
TvY486_0705620 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
TvY486_1117110 ⚠
cAMP response protein 1, putative
— OG7
TvY486_1104700 ⚠
protein kinase A regulatory subunit
— OG7
TvY486_1105780 ⚠
hypothetical protein, conserved
— OG7
TvY486_1103940 ⚠
leucyl-tRNA synthetase, putative
— OG7
TvY486_0703120 ⚠
translation initiation factor IF-2, putative
— OG7
TvY486_0806480 ⚠
translation initiation factor IF-2, putative
— OG7
TvY486_0903000 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0400720 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.