TvY486_0806610

Component of IIS longevity pathway SMK-1, putative
Trypanosoma vivax Y486 OG6: OG6_137892 OG7: OG7_0004683 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0043440 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0301870 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_1008580 ⚠
rab-like GTPase activating protein, putative
— Both
TvY486_0603870 ⚠
valyl-tRNA synthetase, putative
— Both
TvY486_0302590 ⚠
NOL1/NOP2/sun family, putative
— Both
TvY486_0303980 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
TvY486_0400720 ⚠
hypothetical protein, conserved
— Both
TvY486_0805330 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— Both
TvY486_0700740 ⚠
protein kinase C substrate protein, heavy cha
— Both
TvY486_1107020 ⚠
hypothetical protein, conserved
— Both
TvY486_0705610 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
TvY486_0705620 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
TvY486_0702080 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0200730 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TvY486_0400470 ⚠
AP-1 adapter complex gamma subunit, putative
— Both
TvY486_0703120 ⚠
translation initiation factor IF-2, putative
— Both
TvY486_0200380 ⚠
Glycerophosphoryl diester phosphodiesterase f
— Both
TvY486_0600210 ⚠
alanyl-tRNA synthetase, putative
— Both
TvY486_1109070 ⚠
ribonuclease II-like protein, putative, (frag
— Both
TvY486_0200720 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
TvY486_0706770 ⚠
hypothetical protein, conserved
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1108060 ⚠
rrp44p homologue, putative
— OG7
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_0602440 ⚠
epsilon-adaptin, putative, AP-1/4 adapter com
— OG7
TvY486_0900740 ⚠
serine/threonine protein kinase, putative
— OG7
TvY486_0806480 ⚠
translation initiation factor IF-2, putative
— OG7
TvY486_0906200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0702240 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
TvY486_0804920 ⚠
tyrosyl/methionyl-tRNA synthetase, putative
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1008540 ⚠
rab-like GTPase activating protein, putative
— OG7
TvY486_0402970 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TvY486_0601610 ⚠
NUDC-like protein, putative, nuclear movement
— OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1107000 ⚠
cytochrome b5, putative
— OG7
TvY486_1114490 ⚠
cytochrome b5, putative
— OG7
TvY486_0706130 ⚠
protein kinase, putative
— OG7
TvY486_0201800 ⚠
protein kinase, putative
— OG7
TvY486_1012630 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TvY486_0404250 ⚠
dihydrouridine synthase, putative
— OG7
TvY486_0043450 ⚠
ABC transporter, putative (fragment)
— OG7
TvY486_0801730 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_1003160 ⚠
ABC transporter protein, putative
— OG7
TvY486_0003610 ⚠
cytochrome b, putative
— OG7
TvY486_0401020 ⚠
cleavage and polyadenylation specificity fact
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.