TvY486_0100520

homocysteine S-methyltransferase, putative, (fragment)
Trypanosoma vivax Y486 OG6: OG6_102920 OG7: OG7_0003584 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0705750 ⚠
SET domain containing protein, putative
— OG7
TvY486_1008610
OTU-like cysteine protease, putative
— Both
TvY486_0502140 ⚠
SET domain containing protein, putative
— OG7
TvY486_0300160 ⚠
SET domain containing protein, putative
— OG7
TvY486_0806080 ⚠
SET domain containing protein, putative
— OG7
TvY486_1007940 ⚠
SET domain containing protein, putative
— OG7
TvY486_1010760 ⚠
SET domain containing protein, putative
— OG7
TvY486_0802430 ⚠
SET domain containing protein, putative
— OG7
TvY486_0102090 ⚠
SET domain containing protein, putative
— OG7
TvY486_0905170
EF hand containing protein, putative, calmodu
— OG6
TvY486_0403100 ⚠
TPR repeat/SET domain containing protein, put
— OG7
TvY486_0801450
hypothetical protein, conserved
— OG7
TvY486_1107910 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_1116920 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0906670 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1008540 ⚠
rab-like GTPase activating protein, putative
— OG7
TvY486_1008580 ⚠
rab-like GTPase activating protein, putative
— OG7
TvY486_1109230 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TvY486_0404330 ⚠
adrenodoxin precursor, putative
— Both
TvY486_0700690 ⚠
electron transfer protein, putative
— Both
TvY486_0600780
PITH domain-containing protein
— Both
TvY486_0500300 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0500380 ⚠
hypothetical protein, conserved
— Both
TvY486_0503780 ⚠
serine/threonine protein phosphatase, putativ
— OG6
TvY486_0503790 ⚠
serine/threonine protein phosphatase, putativ
— OG6
TvY486_1115860
Cation efflux family, putative
— Both
TvY486_0304116
leucine-rich repeat-containing protein
— Both
TvY486_0804440
hypothetical protein, conserved
— Both
TvY486_0401460
hypothetical protein, conserved
— OG6
TvY486_1114550
ornithine decarboxylase, putative
— Both
TvY486_0601210
protein kinase, putative, mitogen-activated p
— OG6
TvY486_1015390 ⚠
SET domain containing protein, putative
— Both
TvY486_0402950
Uncharacterised ACR, YggU family COG1872, put
— Both
TvY486_1008410
Sucrase/ferredoxin-like, putative
— Both
TvY486_1101900 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.