TvY486_0600780

PITH domain-containing protein
Trypanosoma vivax Y486 OG6: OG6_102988 OG7: OG7_0006444 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1008410
Sucrase/ferredoxin-like, putative
— Both
TvY486_1109230 ⚠
haloacid dehalogenase-like hydrolase, putativ
— +1 more Both
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_1107910 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0403640 ⚠
Kinesin-13 4, putative
— OG7
TvY486_0403510 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TvY486_1011250
nicotinate phosphoribosyltransferase, putativ
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1107750
hypothetical protein, conserved
— Both
TvY486_0200810 ⚠
transcription elongation factor s-II, putativ
— Both
TvY486_0201540
esterase, putative, (fragment)
— Both
TvY486_1116720 ⚠
iron superoxide dismutase, putative
— Both
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_1115840 ⚠
iron superoxide dismutase, putative
— Both
TvY486_0500540 ⚠
thioredoxin-like protein, putative
— Both
TvY486_0501970
Macro domain containing protein, putative
— Both
TvY486_0703730
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TvY486_1116640 ⚠
superoxide dismutase, putative
— Both
TvY486_0007940 ⚠
tviv623d01.q1k_22, TPR-repeat protein, putati
— OG6
TvY486_0302960
U-box domain containing protein, putative
— Both
TvY486_0503540
hypothetical protein, conserved
— Both
TvY486_1115680 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0100550 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TvY486_0802980
mitogen-activated protein kinase 3, putative
— OG6
TvY486_1010310 ⚠
monothiol glutaredoxin, putative
— Both
TvY486_1004460 ⚠
stress-inducible protein STI1-like, putative
— OG6
TvY486_0805170
dihydroorotase, putative
— Both
TvY486_1004990 ⚠
protein phosphatase 2C-like, putative
— OG6
TvY486_1005070 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TvY486_0502590
hypothetical protein, conserved
— Both
TvY486_0800330
serine/threonine kinase, putative
— OG6
TvY486_1110870
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TvY486_0402570
pyroglutamyl-peptidase I, putative
— Both
TvY486_1005340
eukaryotic translation initiation factor 6 (e
— Both
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0502810 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TvY486_0201650 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0803180
Mitogen-activated protein kinase 10, putative
— OG6
TvY486_0304700
UBX domain-containing protein
— Both
TvY486_0801610
hypothetical protein, conserved
— Both
TvY486_0018200 ⚠
kinesin, putative
— OG7
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_1105090 ⚠
transcription elongation factor, putative
— OG7
TvY486_0901070 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0400060 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
TvY486_1112790 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TvY486_1005030 ⚠
ubiquitin-like protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.