TvY486_1015470

Eukaryotic translation initiation factor 4E-2
Trypanosoma vivax Y486 OG6: OG6_101698 OG7: OG7_0002303 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0302960 ⚠
U-box domain containing protein, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0005970 ⚠
5'-3' exonuclease, putative
— OG7
TvY486_0704970 ⚠
5'-3' exoribonuclease A, putative
— OG7
TvY486_1006180 ⚠
5'-3' exoribonuclease D, putative
— OG7
TvY486_0304750 ⚠
hypothetical protein, conserved
— OG7
TvY486_0601580 ⚠
pdz domain containing protein, putative
— OG7
TvY486_0021110 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TvY486_1009730 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TvY486_0701820 ⚠
GMP synthase [glutamine-hydrolysing], (fragme
— OG7
TvY486_1109390 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TvY486_0305050 ⚠
nuclear transcription factor, putative
— OG7
TvY486_0701770 ⚠
R3H domain containing protein, putative
— OG7
TvY486_0900800 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TvY486_1109330 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1106730 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1007580 ⚠
protein transport protein Sec23A, putative
— OG7
TvY486_0804660 ⚠
hypothetical protein, conserved
— OG7
TvY486_1011250 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TvY486_0805420 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TvY486_0800270 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0010920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1114840 ⚠
Outer row dynein-assembly protein 7
— OG7
TvY486_0700500 ⚠
hypothetical protein, conserved
— OG7
TvY486_1109550 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TvY486_0301890 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TvY486_1007260 ⚠
ATP-dependent DEAD/H RNA helicae, putative
— OG7
TvY486_0501330 ⚠
ecotin, putative
— OG7
TvY486_0501230 ⚠
Ecotin-like protein
— OG7
TvY486_0702980 ⚠
small nuclear ribonucleoprotein, putative, Sm
— OG7
TvY486_1102350 ⚠
phenylalanyl-tRNA synthetase, putative, (frag
— OG7
TvY486_1005030 ⚠
ubiquitin-like protein, putative
— OG7
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG7
TvY486_1101230 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TvY486_0404130 ⚠
diphthine synthase, putative
— OG7
TvY486_1105240 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG7
TvY486_1002630 ⚠
CS domain containing protein, putative
— OG7
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TvY486_1116490 ⚠
poly(A) polymerase, putative
— OG7
TvY486_1110550 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TvY486_0904790 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TvY486_0300670 ⚠
NPL4 family, putative
— OG7
TvY486_1013280 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TvY486_0703730 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TvY486_1112720 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TvY486_1106720 ⚠
MRB1-associated protein
— OG7
TvY486_0900010 ⚠
Nucleoporin NUP92
— OG7
TvY486_0600460 ⚠
cysteinyl-tRNA synthetase, putative, (fragmen
— OG7
TvY486_1104780 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
TvY486_1103355 ⚠
DNA polymerase A, putative (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.