TvY486_1101230

UBA/TS-N domain containing protein, putative
Trypanosoma vivax Y486 OG6: OG6_129093 OG7: OG7_0004831 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TvY486_0300390 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TvY486_0043450 ⚠
ABC transporter, putative (fragment)
— OG7
TvY486_1005070 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TvY486_0800330
serine/threonine kinase, putative
— OG6
TvY486_0502590 ⚠
hypothetical protein, conserved
— Both
TvY486_0300560 ⚠
TAP42-like family, putative
— Both
TvY486_1110870 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TvY486_1110420 ⚠
Nucleoporin NUP119
— Both
TvY486_0402570 ⚠
pyroglutamyl-peptidase I, putative
— Both
TvY486_1005340 ⚠
eukaryotic translation initiation factor 6 (e
— Both
TvY486_1013710 ⚠
N-myristoyl transferase, putative
— Both
TvY486_1013590 ⚠
pyruvate kinase 1, putative, (fragment)
— Both
TvY486_1013080
zinc metallopeptidase, putative
— OG6
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_1110430 ⚠
Nucleoporin NUP119
— Both
TvY486_0800240 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0301440 ⚠
hypothetical protein, conserved
— Both
TvY486_0803180
Mitogen-activated protein kinase 10, putative
— OG6
TvY486_0201650 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0304700 ⚠
UBX domain-containing protein
— Both
TvY486_1008430 ⚠
hypothetical protein, conserved
— Both
TvY486_0038700 ⚠
ubiquitin hydrolase, putative
— Both
TvY486_0403510 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TvY486_1011250 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0200810 ⚠
transcription elongation factor s-II, putativ
— Both
TvY486_0018200 ⚠
kinesin, putative
— OG7
TvY486_1103360 ⚠
Kinesin-13 5, putative
— OG7
TvY486_0901210 ⚠
Kinesin-13 1, putative (fragment)
— OG7
TvY486_0403640 ⚠
Kinesin-13 4, putative
— OG7
TvY486_1102690 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— OG7
TvY486_0007960 ⚠
aldo-keto reductase, putative
— OG7
TvY486_1106650 ⚠
pyruvate phosphate dikinase, putative
— OG7
TvY486_0400470 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
TvY486_1003730 ⚠
proteasome activator protein pa26, putative
— OG7
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_0101100 ⚠
beta tubulin, putative, (fragment)
— OG7
TvY486_0101130 ⚠
alpha tubulin, putative
— OG7
TvY486_0101140 ⚠
beta tubulin, putative
— OG7
TvY486_0300320 ⚠
tubulin gamma chain (fragment)
— OG7
TvY486_1111860 ⚠
tubulin delta chain
— OG7
TvY486_0101150 ⚠
alpha tubulin, putative, (fragment)
— OG7
TvY486_1116490 ⚠
poly(A) polymerase, putative
— OG7
TvY486_0601320 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TvY486_0901070 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1109490 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.