TvY486_1013590

pyruvate kinase 1, putative, (fragment)
Trypanosoma vivax Y486 OG6: OG6_100258 OG7: OG7_0002165 163 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 163 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0703730
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0901060
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TvY486_0805760
transketolase, putative
— Both
TvY486_1006840 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TvY486_0902890 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TvY486_0704690
nucleoside hydrolase, putative
— Both
TvY486_0604230 ⚠
S-adenosylmethionine synthetase, putative, (f
— Both
TvY486_0045510 ⚠
S-adenosylmethionine synthetase, putative (fr
— Both
TvY486_0604250 ⚠
S-adenosylmethionine synthetase, putative, (f
— Both
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TvY486_0500500 ⚠
NADH-dependent fumarate reductase, putative
— Both
TvY486_0901840 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TvY486_1003670 ⚠
NADH-dependent fumarate reductase, putative
— Both
TvY486_0904290 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TvY486_0604240 ⚠
S-adenosylmethionine synthetase, putative, (f
— Both
TvY486_0604210 ⚠
S-adenosylmethionine synthetase, putative, (f
— Both
TvY486_0030550 ⚠
S-adenosylmethionine synthetase (fragment)
— Both
TvY486_0019810 ⚠
fatty acyl CoA syntetase 1, putative
— Both
TvY486_0039420 ⚠
cyclic nucleotide phosphodiesterase (fragment
— Both
TvY486_0030535 ⚠
S-adenosylmethionine synthetase, putative, (f
— Both
TvY486_0401040
aldose 1-epimerase, putative
— Both
TvY486_0705520
dihydrofolate reductase-thymidylate synthase,
— Both
TvY486_1003210 ⚠
fatty acyl CoA synthetase, putative
— Both
TvY486_0901440 ⚠
fatty acyl CoA synthetase 3, putative, (fragm
— Both
TvY486_1117780
glucosamine-6-phosphate isomerase, putative
— Both
TvY486_0901790 ⚠
cAMP-specific phosphodiesterase, putative
— Both
TvY486_0806260
guanine deaminase, putative
— Both
TvY486_0603710 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TvY486_0602450 ⚠
pseudouridine synthase A-like protein, putati
— Both
TvY486_0100940 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TvY486_1116090
hypothetical protein, conserved
— Both
TvY486_0601230
phosphatase 2C, putative
— OG6
TvY486_1108250
electron-transfer-flavoprotein, alpha polypep
— Both
TvY486_0500930
alanine racemase, putative
— Both
TvY486_0043640
SEP domain containing protein, putative
— Both
TvY486_0101330 ⚠
amidohydrolase, putative
— Both
TvY486_0101320 ⚠
amidohydrolase, putative
— Both
TvY486_1109390
tRNA threonylcarbamoyl adenosine modification
— Both
TvY486_1107910 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0601320 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TvY486_1005030 ⚠
ubiquitin-like protein, putative
— OG7
TvY486_0005970 ⚠
5'-3' exonuclease, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0702090 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TvY486_0007960 ⚠
aldo-keto reductase, putative
— OG7
TvY486_0400470 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.