TvY486_0005970

5'-3' exonuclease, putative
Trypanosoma vivax Y486 OG6: OG6_156818 OG7: OG7_0003221 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1001510 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
TvY486_1116090 ⚠
hypothetical protein, conserved
— OG7
TvY486_0702090 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0304700 ⚠
UBX domain-containing protein
— OG7
TvY486_1000070 ⚠
Kinetoplast poly(A) polymerase 2
— OG7
TvY486_1101230 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TvY486_0701820 ⚠
GMP synthase [glutamine-hydrolysing], (fragme
— OG7
TvY486_0200350 ⚠
phosphatidylinositol kinase domain protein, p
— OG7
TvY486_0400510 ⚠
TOR-like 1
— OG7
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_1115410 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TvY486_0804660 ⚠
hypothetical protein, conserved
— OG7
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0301240 ⚠
General negative regulator of transcription s
— OG7
TvY486_1013490 ⚠
tubulin-specific chaperone, putative
— OG7
TvY486_0803810 ⚠
translation initiation factor eif-2b beta sub
— OG7
TvY486_0402010 ⚠
Sec7 domain containing protein, putative
— OG7
TvY486_0804880 ⚠
WW domain containing protein, putative
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0032990 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1103500 ⚠
ubiquitin-transferase, putative
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1001080 ⚠
dynein arm light chain, putative
— OG7
TvY486_0700600 ⚠
dynein arm light chain, axonemal, putative
— OG7
TvY486_1000730 ⚠
structural maintenance of chromosome
— OG7
TvY486_0600830 ⚠
hypothetical protein, conserved
— OG7
TvY486_1010170 ⚠
structural maintenance of chromosome 2, putat
— OG7
TvY486_1015130 ⚠
hypothetical protein, conserved
— OG7
TvY486_0804320 ⚠
hypothetical protein, conserved
— OG7
TvY486_0201490 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0002640 ⚠
microtubule-associated protein, putative, (fr
— OG7
TvY486_1002420 ⚠
Tetratricopeptide repeat, putative
— OG7
TvY486_1014170 ⚠
fibrillarin, putative
— OG7
TvY486_1104640 ⚠
hypothetical protein, conserved
— OG7
TvY486_0033220 ⚠
microtubule-associated protein, putative, (fr
— OG7
TvY486_0503450 ⚠
hypothetical protein, conserved
— OG7
TvY486_0905570 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TvY486_1104700 ⚠
protein kinase A regulatory subunit
— OG7
TvY486_0703970 ⚠
tc40 antigen-like, putative, immunodominant a
— OG7
TvY486_0600790 ⚠
translation initiation factor EIF-2b alpha su
— OG7
TvY486_1105240 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG7
TvY486_1003700 ⚠
aspartate aminotransferase, putative
— OG7
TvY486_1003680 ⚠
aspartate aminotransferase, putative, (fragme
— OG7
TvY486_1112580 ⚠
DNA topoisomerase II, putative, (fragment)
— OG7
TvY486_0706530 ⚠
hypothetical protein, conserved
— OG7
TvY486_1105090 ⚠
transcription elongation factor, putative
— OG7
TvY486_0701420 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.