TvY486_0701420

C-1-tetrahydrofolate synthase, cytoplasmic, putative
Trypanosoma vivax Y486 OG6: OG6_100216 OG7: OG7_0002739 217 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 217 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0807730 ⚠
amino acid transporter
— OG6
TvY486_0200730 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
TvY486_0404360 ⚠
calreticulin, putative
— OG6
TvY486_0702080 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_0705620 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
TvY486_0705610 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
TvY486_0805130 ⚠
transaldolase, putative
— Both
TvY486_1107020 ⚠
hypothetical protein, conserved
— OG6
TvY486_0701820 ⚠
GMP synthase [glutamine-hydrolysing], (fragme
— Both
TvY486_0700740 ⚠
protein kinase C substrate protein, heavy cha
— OG6
TvY486_1103940 ⚠
leucyl-tRNA synthetase, putative
— OG6
TvY486_0805330 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— OG6
TvY486_0804660 ⚠
hypothetical protein, conserved
— Both
TvY486_0602140 ⚠
importin alpha, putative
— OG6
TvY486_0400720 ⚠
hypothetical protein, conserved
— OG6
TvY486_0303980 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— OG6
TvY486_0026450 ⚠
transmembrane amino acid transporter protein
— OG6
TvY486_1006180 ⚠
5'-3' exoribonuclease D, putative
— Both
TvY486_0603870 ⚠
valyl-tRNA synthetase, putative
— OG6
TvY486_0801610 ⚠
hypothetical protein, conserved
— Both
TvY486_0302590 ⚠
NOL1/NOP2/sun family, putative
— OG6
TvY486_0502810 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TvY486_1101230 ⚠
UBA/TS-N domain containing protein, putative
— Both
TvY486_0201650 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0304700 ⚠
UBX domain-containing protein
— Both
TvY486_0803180 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
TvY486_1008580 ⚠
rab-like GTPase activating protein, putative
— OG6
TvY486_0036380 ⚠
hypothetical protein, conserved
— Both
TvY486_0706570 ⚠
trans-sialidase, putative, (fragment)
— OG6
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TvY486_0101370 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG6
TvY486_0039990 ⚠
trans-sialidase, putative
— OG6
TvY486_0038450 ⚠
trans-sialidase, putative
— OG6
TvY486_1012800 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TvY486_1100840 ⚠
Nuclear pore complex protein 158
— OG6
TvY486_0704970 ⚠
5'-3' exoribonuclease A, putative
— Both
TvY486_0403750 ⚠
amino acid transporter, putative
— OG6
TvY486_1115520 ⚠
phosphomannose isomerase, putative
— Both
TvY486_1001500 ⚠
methionyl-tRNA synthetase, putative, (fragmen
— OG6
TvY486_0703520 ⚠
tyrosyl-tRNA synthetase, putative
— OG6
TvY486_0901060 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TvY486_0301440 ⚠
hypothetical protein, conserved
— Both
TvY486_0301870 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_1116090 ⚠
hypothetical protein, conserved
— Both
TvY486_0706370 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG6
TvY486_1006890 ⚠
serine peptidase, Clan SC, Family S9B (fragme
— OG6
TvY486_1117420 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TvY486_1011250 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TvY486_1014910 ⚠
ABC transporter, putative
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.