TvY486_1115520

phosphomannose isomerase, putative
Trypanosoma vivax Y486 OG6: OG6_102059 OG7: OG7_0006704 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0403510 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TvY486_0001560
ChaC-like protein
— Both
TvY486_0601580
pdz domain containing protein, putative
— Both
TvY486_0404230 ⚠
amino acid transporter, putative
— OG6
TvY486_0701420 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TvY486_0807690 ⚠
amino acid transporter
— OG6
TvY486_0807050 ⚠
amino acid transporter, putative
— OG6
TvY486_0024100 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TvY486_1116770 ⚠
amino acid transporter, putative
— OG6
TvY486_0807700 ⚠
amino acid transporter
— OG6
TvY486_0800800 ⚠
amino acid transporter, putative
— OG6
TvY486_0403750 ⚠
amino acid transporter, putative
— OG6
TvY486_0807730 ⚠
amino acid transporter
— OG6
TvY486_0026450 ⚠
transmembrane amino acid transporter protein
— OG6
TvY486_0804660
hypothetical protein, conserved
— Both
TvY486_0701820
GMP synthase [glutamine-hydrolysing], (fragme
— Both
TvY486_1116420
hypothetical protein, conserved
— Both
TvY486_0805130
transaldolase, putative
— Both
TvY486_0704970 ⚠
5'-3' exoribonuclease A, putative
— Both
TvY486_1006180 ⚠
5'-3' exoribonuclease D, putative
— Both
TvY486_0906570
hypothetical protein, conserved
— Both
TvY486_0300370 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
TvY486_0603340
RNA-binding protein, putative, SGN1, putative
— OG6
TvY486_1109230 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TvY486_1105240 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TvY486_1003700 ⚠
aspartate aminotransferase, putative
— Both
TvY486_1003680 ⚠
aspartate aminotransferase, putative, (fragme
— Both
TvY486_0602440 ⚠
epsilon-adaptin, putative, AP-1/4 adapter com
— Both
TvY486_0033800
protein phosphatase 2C, putative (fragment)
— OG6
TvY486_1116090
hypothetical protein, conserved
— Both
TvY486_1108250
electron-transfer-flavoprotein, alpha polypep
— Both
TvY486_0500930
alanine racemase, putative
— Both
TvY486_0043640
SEP domain containing protein, putative
— Both
TvY486_1109390
tRNA threonylcarbamoyl adenosine modification
— Both
TvY486_0901060
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TvY486_0038700 ⚠
ubiquitin hydrolase, putative
— Both
TvY486_0035050 ⚠
iron/ascorbate oxidoreductase family protein
— OG7
TvY486_1112790 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1109490 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TvY486_1007580
protein transport protein Sec23A, putative
— OG7
TvY486_0702090 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TvY486_1110250 ⚠
eukaryotic translation initiation factor, put
— OG7
TvY486_1000070 ⚠
Kinetoplast poly(A) polymerase 2
— OG7
TvY486_0006470 ⚠
oxidoreductase, putative
— OG7
TvY486_0901070 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0601850
adenosine kinase, putative
— OG7
TvY486_1113190 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TvY486_0005970 ⚠
5'-3' exonuclease, putative
— OG7
TvY486_1105090 ⚠
transcription elongation factor, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.